Functional heterogeneity in liver and lung macrophages

DL Laskin, B Weinberger… - Journal of leukocyte …, 2001 - academic.oup.com
Although initially considered merely “scavenger cells” that participate in immunologic
responses only after B and T lymphocytes have performed their biological tasks, more recent …

Liver macrophages in healthy and diseased liver

Z Abdullah, PA Knolle - Pflügers Archiv-European Journal of Physiology, 2017 - Springer
Kupffer cells, the largest tissue resident macrophage population, are key for the
maintenance of liver integrity and its restoration after injury and infections, as well as the …

Dynamic plasticity of macrophage functions in diseased liver

T Ritz, O Krenkel, F Tacke - Cellular immunology, 2018 - Elsevier
Liver macrophages attract increasing interest due to their crucial roles in homeostasis and
hepatic diseases. Recent findings in mice and man suggest a remarkable phenotypic and …

Hepatic macrophages in homeostasis and liver diseases: from pathogenesis to novel therapeutic strategies

C Ju, F Tacke - Cellular & molecular immunology, 2016 - nature.com
Macrophages represent a major cell type of innate immunity and have emerged as a critical
player and therapeutic target in many chronic inflammatory diseases. Hepatic macrophages …

The isolation and characterization of murine macrophages

X Zhang, R Goncalves… - Current protocols in …, 2008 - Wiley Online Library
Macrophages are mononuclear phagocytes that are widely distributed throughout the body.
These cells can contribute to development and homeostasis and participate in innate and …

The isolation and characterization of murine macrophages

R Gonçalves, DM Mosser - Current protocols in immunology, 2015 - Wiley Online Library
Macrophages are mononuclear phagocytes that are widely distributed throughout the body.
These cells can contribute to development and homeostasis and participate in innate and …

Macrophages: sentinels and regulators of the immune system

L Franken, M Schiwon, C Kurts - Cellular microbiology, 2016 - Wiley Online Library
The important role of macrophages in host defense against a variety of pathogens has long
been recognized and has been documented and reviewed in numerous publications …

Macrophage heterogeneity in tissues: phenotypic diversity and functions

S Gordon, A Plüddemann… - Immunological …, 2014 - Wiley Online Library
During development and throughout adult life, macrophages derived from hematopoietic
progenitors are seeded throughout the body, initially in the absence of inflammatory and …

The macrophage

S Gordon - Bioessays, 1995 - Wiley Online Library
The macrophage plays an important role in host development and physiology, and in
pathogenesis of many infectious, immunologic and degenerative disease processes. It …

Macrophages: current views on their differentiation, structure, and function

JM Papadimitriou, RB Ashman - Ultrastructural pathology, 1989 - Taylor & Francis
Macrophages are large mononuclear phagocytes that represent the major differentiated
elements of the mononuclear phagocytic system. They arise from distinct progenitors in the …