Amyloid plaques contain many proteins in addition to beta amyloid (Aβ). Previous studies
examining plaque-associated proteins have shown these additional proteins are important; …

Rapidly progressive Alzheimer's disease (rpAD) is a particularly aggressive form of
Alzheimer's disease, with a median survival time of 7–10 months after diagnosis. Why these …

Introduction We investigated the proteomic profiles of amyloid plaques (APs) from
Alzheimer's disease (AD) and age-matched non-AD brains and APP/PS1 transgenic model …

The presence of amyloid plaques in the brain is one of the pathological hallmarks of
Alzheimer's disease (AD). We report here a comprehensive proteomic analysis of senile …

Despite a key role of amyloid‐beta (Aβ) in Alzheimer's disease (AD), mechanisms that link
Aβ plaques to tau neurofibrillary tangles and cognitive decline still remain poorly …

Alzheimer's disease (AD) is pathologically defined by the presence of fibrillar amyloid β (Aβ)
peptide in extracellular senile plaques and tau filaments in intracellular neurofibrillary …

Amyloid-beta (Aβ) plays a key role in the pathogenesis of Alzheimer's disease (AD), but little
is known about the proteoforms present in AD brain. We used high-resolution mass …

Neurodegenerative diseases are often defined pathologically by the presence of protein
aggregates. These aggregates, including amyloid plaques in Alzheimer's disease (AD) …

Cortical amyloid-beta (Aβ) deposition is considered essential in Alzheimer's disease (AD)
and is also detectable in nondemented individuals with pathologic aging (PA). The present …

Accumulation and deposition of β-amyloid peptide, a major constituent in neuritic plaques
are hallmarks of Alzheimer's disease (AD) and AD-related neurodegenerative diseases. β …