Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …

White adipose tissue (WAT) is a major endocrine and secretory organ, which releases a
wide range of protein signals and factors termed adipokines. A number of adipokines …

Obesity plays a causative role in the pathogenesis of the metabolic syndrome. Adipokines
may link obesity to its co-morbidities. Most adipokines with pro-inflammatory properties are …

Several lines of preclinical and clinical research have confirmed that chronic low-grade
inflammation of adipose tissue is mechanistically linked to metabolic disease and organ …

The worldwide obesity epidemic has become a major health concern, because it contributes
to higher mortality due to an increased risk for noncommunicable diseases including …

Context Adipose tissue is increasingly recognized as an active endocrine organ with many
secretory products and part of the innate immune system. With obesity, macrophages …

Metabolic syndrome is a major risk factor for cardiovascular and metabolic diseases. Playing
a central role in the development of metabolic syndrome and in its clinical consequences is …

Obesity is frequently associated with chronic inflammation, metabolic and vascular
alterations which predispose to the development of the Metabolic Syndrome (MetS) …

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The incidence of obesity has increased dramatically during recent decades. Obesity will
cause a decline in life expectancy for the first time in recent history due to numerous co …