[HTML][HTML] Quantifying Brain and Cognitive Maintenance as Key Indicators for Sustainable Cognitive Aging: Insights from the UK Biobank

L Lin, M Xiong, Y Jin, W Kang, S Wu, S Sun, Z Fu - Sustainability, 2023 - mdpi.com
Age-related cognitive decline is a global phenomenon that affects individuals worldwide.
The course and extent of this decline are influenced by numerous factors, such as genetics …

[HTML][HTML] The Protective Power of Cognitive Reserve: Examining White Matter Integrity and Cognitive Function in the Aging Brain for Sustainable Cognitive Health

L Lin, Y Jin, M Xiong, S Wu, S Sun - Sustainability, 2023 - mdpi.com
Sustainable cognitive health is heavily influenced by cognitive reserve (CR), which delays
cognitive decline or reduces its severity by enhancing cognitive function through life …

Prediction of brain age and cognitive age: Quantifying brain and cognitive maintenance in aging

M Anatürk, T Kaufmann, JH Cole, S Suri… - Human brain …, 2021 - Wiley Online Library
The concept of brain maintenance refers to the preservation of brain integrity in older age,
while cognitive reserve refers to the capacity to maintain cognition in the presence of …

[HTML][HTML] Exploring Successful Cognitive Aging: Insights Regarding Brain Structure, Function, and Demographics

X Xu, L Lin, S Wu, S Sun - Brain Sciences, 2023 - mdpi.com
In the realm of cognitive science, the phenomenon of “successful cognitive aging” stands as
a hallmark of individuals who exhibit cognitive abilities surpassing those of their age …

[HTML][HTML] Association of Cognitive Reserve Indicator with Cognitive Decline and Structural Brain Differences in Middle and Older Age: Findings from the UK Biobank

W Yang, J Wang, J Guo, A Dove, X Qi… - The Journal of …, 2024 - Springer
Background Cognitive reserve (CR) contributes to preserving cognition when facing brain
aging and damage. CR has been linked to dementia risk in late life. However, the …

[HTML][HTML] Potentially modifiable lifestyle factors, cognitive reserve, and cognitive function in later life: A cross-sectional study

L Clare, YT Wu, JC Teale, C MacLeod… - PLoS …, 2017 - journals.plos.org
Background Potentially modifiable lifestyle factors may influence cognitive health in later life
and offer potential to reduce the risk of cognitive decline and dementia. The concept of …

The metabolic brain signature of cognitive resilience in the 80+: beyond Alzheimer pathologies

EM Arenaza-Urquijo, SA Przybelski, TL Lesnick… - Brain, 2019 - academic.oup.com
Research into cognitive resilience imaging markers may help determine the clinical
significance of Alzheimer's disease pathology among older adults over 80 years (80+). In …

[HTML][HTML] What does the brain have to keep working at its best? Resilience mechanisms such as antioxidants and brain/cognitive reserve for counteracting Alzheimer's …

DM Cammisuli, F Franzoni, G Scarfò, J Fusi, M Gesi… - Biology, 2022 - mdpi.com
Simple Summary Alzheimer's disease currently represents one of the major challenges of
modern society in relation to social and medical costs. As people age, they often experience …

[HTML][HTML] Predicting cognitive resilience from midlife lifestyle and multi-modal MRI: a 30-year prospective cohort study

A Topiwala, S Suri, C Allan, V Valkanova, N Filippini… - PLoS …, 2019 - journals.plos.org
Background There is significant heterogeneity in the clinical expression of structural brain
abnormalities, including Alzheimer's disease biomarkers. Some individuals preserve their …

Exploring the secrets of super-aging: a UK Biobank study on brain health and cognitive function

BS Klinedinst, MK Kharate, P Mohammadiarvejeh… - GeroScience, 2023 - Springer
Communities across the globe are faced with a rapidly aging society, where age is the main
risk factor for cognitive decline and development of Alzheimer's and related diseases …