Background The purpose of this study was to investigate the relationship between biofilm-
forming microorganisms (BFM) and DEFB1 gene variants on β-defensin levels in patients …

In this study, the difference in expression of human beta-defensin-3 in periprosthetic tissue
and cancellous bone was observed in the periprosthetic tissue and cancellous bone of …

Background The alpha-defensin test has been previously demonstrated to be highly
accurate in the diagnosis of prosthetic joint infection (PJI), nearly matching the …

Background: Periprosthetic joint infection (PJI) is the most common complication after
artificial joint replacement as previously reported. However, the main problem at present is …

The utility of α-defensin (AD), leukocyte esterase (LE) levels, and metagenomics sequencing
as diagnostic tools for prosthetic joint infection (PJI) has been suggested, but there are few …

Background: Differentiation between septic and aseptic loosening of joint replacements is
essential for successful revision surgery, but reliable markers for the diagnosis of low-grade …

Periprosthetic joint infection (PJI) is a serious complication that may occur after native joint
replacement leading to a severe health and economic burden. Currently, due to several …

Results: In the case of the icaADBC operon, single nucleotide polymorphisms (SNPs) in the
icaADBC regulatory region allowed clustering of the strains in five groups from which a …

Background Previous studies have demonstrated that the administration of antibiotics to
patients before performing diagnostic testing for periprosthetic joint infection (PJI) can …

Musculoskeletal Infection Society's (MSIS) definition of periprosthetic joint infection [2, 5]. By
combining many of the indirect tests for detecting PJI, a common method to define and …