A validated mathematical model of the cytokine release syndrome in severe COVID-19

RF Reis, AB Pigozzo, CRB Bonin… - Frontiers in molecular …, 2021 - frontiersin.org
By June 2021, a new contagious disease, the Coronavirus disease 2019 (COVID-19), has
infected more than 172 million people worldwide, causing more than 3.7 million deaths …

Modeling the within-host dynamics of SARS-CoV-2 infection based on antiviral treatment

T Song, Y Wang, X Gu, S Qiao - Mathematics, 2023 - mdpi.com
The COVID-19 pandemic has highlighted the profound impact of the SARS-CoV-2 virus as a
significant threat to human health. There is an urgent need to develop a comprehensive …

The good, the bad and the ugly: A mathematical model investigates the differing outcomes among CoVID-19 patients

S Sahoo, S Jhunjhunwala, MK Jolly - Journal of the Indian Institute of …, 2020 - Springer
The disease caused by SARS-CoV-2—CoVID-19—is a global pandemic that has brought
severe changes worldwide. Approximately 80% of the infected patients are largely …

Modeling the viral dynamics of SARS-CoV-2 infection

S Wang, Y Pan, Q Wang, H Miao, AN Brown… - Mathematical …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the
infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is spreading …

Within host dynamics of SARS-CoV-2 in humans: Modeling immune responses and antiviral treatments

I Ghosh - SN Computer Science, 2021 - Springer
In December 2019, a newly discovered SARS-CoV-2 virus was emerged from China and
propagated worldwide as a pandemic, resulting in about 3–5% mortality. Mathematical …

Mathematical modeling of interaction between innate and adaptive immune responses in COVID‐19 and implications for viral pathogenesis

SQ Du, W Yuan - Journal of medical virology, 2020 - Wiley Online Library
We have applied mathematical modeling to investigate the infections of the ongoing
coronavirus disease‐2019 (COVID‐19) pandemic caused by SARS‐CoV‐2 virus. We first …

Dynamical modelling of viral infection and cooperative immune protection in COVID-19 patients

Z Zhou, D Li, Z Zhao, S Shi, J Wu, J Li… - PLOS Computational …, 2023 - journals.plos.org
Once challenged by the SARS-CoV-2 virus, the human host immune system triggers a
dynamic process against infection. We constructed a mathematical model to describe host …

In-host mathematical modelling of COVID-19 in humans

EA Hernandez-Vargas, JX Velasco-Hernandez - Annual reviews in control, 2020 - Elsevier
COVID-19 pandemic has underlined the impact of emergent pathogens as a major threat to
human health. The development of quantitative approaches to advance comprehension of …

Computational simulations to dissect the cell immune response dynamics for severe and critical cases of SARS-CoV-2 infection

R Blanco-Rodriguez, X Du… - Computer methods and …, 2021 - Elsevier
Background: COVID-19 is a global pandemic leading to high death tolls worldwide day by
day. Clinical evidence suggests that COVID-19 patients can be classified as non-severe …

[HTML][HTML] A mathematical model for the within-host (re) infection dynamics of SARS-CoV-2

L Schuh, PV Markov, VM Veliov, NI Stilianakis - Mathematical Biosciences, 2024 - Elsevier
Interactions between SARS-CoV-2 and the immune system during infection are complex.
However, understanding the within-host SARS-CoV-2 dynamics is of enormous importance …