[HTML][HTML] Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer
RN Ramos, Y Missolo-Koussou, Y Gerber-Ferder… - Cell, 2022 - Elsevier
Macrophage infiltration is a hallmark of solid cancers, and overall macrophage infiltration
correlates with lower patient survival and resistance to therapy. Tumor-associated …
correlates with lower patient survival and resistance to therapy. Tumor-associated …
[HTML][HTML] Cancer-associated fibroblasts and tumor-associated macrophages in cancer and cancer immunotherapy
Our understanding of the tumor microenvironment (TME), including the interplay between
tumor cells, stromal cells, immune cells, and extracellular matrix components, is mandatory …
tumor cells, stromal cells, immune cells, and extracellular matrix components, is mandatory …
Targeting folate receptor β positive tumor-associated macrophages in lung cancer with a folate-modified liposomal complex
Y Tie, H Zheng, Z He, J Yang, B Shao, L Liu… - Signal transduction and …, 2020 - nature.com
Tumor-associated macrophages (TAMs) facilitate cancer progression by promoting tumor
invasion, angiogenesis, metastasis, inflammatory responses, and immunosuppression …
invasion, angiogenesis, metastasis, inflammatory responses, and immunosuppression …
Lipid-associated macrophages are induced by cancer-associated fibroblasts and mediate immune suppression in breast cancer
Tumor-associated macrophages (TAM) play a detrimental role in triple-negative breast
cancer (TNBC). In-depth analysis of TAM characteristics and interactions with stromal cells …
cancer (TNBC). In-depth analysis of TAM characteristics and interactions with stromal cells …
Folate receptor beta designates immunosuppressive tumor-associated myeloid cells that can be reprogrammed with folate-targeted drugs
GM Cresswell, B Wang, EM Kischuk, MM Broman… - Cancer research, 2021 - AACR
Although immunotherapies of tumors have demonstrated promise for altering the
progression of malignancies, immunotherapies have been limited by an …
progression of malignancies, immunotherapies have been limited by an …
Characterization of macrophage-cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer
Tumor heterogeneity may broadly influence the activation of tumor-associated
macrophages. We aimed to dissect how breast cancer cells of different molecular …
macrophages. We aimed to dissect how breast cancer cells of different molecular …
Monocyte heterogeneity and functions in cancer
Monocytes are innate immune cells of the mononuclear phagocyte system that have
emerged as important regulators of cancer development and progression. Our …
emerged as important regulators of cancer development and progression. Our …
[HTML][HTML] The dark side of fibroblasts: cancer-associated fibroblasts as mediators of immunosuppression in the tumor microenvironment
L Monteran, N Erez - Frontiers in immunology, 2019 - frontiersin.org
Cancer-associated fibroblasts (CAFs) are prominent components of the microenvironment in
most types of solid tumors, and were shown to facilitate cancer progression by supporting …
most types of solid tumors, and were shown to facilitate cancer progression by supporting …
Cancer-associated fibroblasts promote immunosuppression by inducing ROS-generating monocytic MDSCs in lung squamous cell carcinoma
Cancer-associated fibroblasts (CAF) represent a functionally heterogeneous population of
activated fibroblasts that constitutes a major component of tumor stroma. Although CAFs …
activated fibroblasts that constitutes a major component of tumor stroma. Although CAFs …
Crosstalk between cancer‐associated fibroblasts and immune cells in cancer
Y An, F Liu, Y Chen, Q Yang - Journal of cellular and molecular …, 2020 - Wiley Online Library
Multiple studies have shown that cancer‐associated fibroblasts (CAFs) play an important
role in tumour progression, including carcinogenesis, invasion, metastasis and the …
role in tumour progression, including carcinogenesis, invasion, metastasis and the …