Abstract The Compensation Related Utilization of Neural Circuits Hypothesis (CRUNCH)
proposes a framework for understanding task-related brain activity changes as a function of …

The human brain undergoes marked structural changes with age including cortical thinning
and reduced connectivity because of the degradation of myelin. Although these changes …

Aging reduces cognitive functions, and such impairments have implications in mental and
motor performance. Cognitive function has been recently linked to the risk of falls in older …

Advancing age affects both cognitive performance and functional brain activity and
interpretation of these effects has led to a variety of conceptual research models without …

Motor cognitive functions and their neurophysiology evolve and degrade along the lifespan
in a dramatic fashion. Current models of how the brain adapts to aging remain inspired …

Neuroimaging data emphasize that older adults often show greater extent of brain activation
than younger adults for similar objective levels of difficulty. A possible interpretation of this …

Motor performance and cognitive function both decline with aging. Older adults for example
are usually less steady for a constant-force task than young adults when performing low …

A reduction in cognitive resources has been originally proposed to account for age-related
decrements in several cognitive domains. According to this view, aging limits the pool of …

Healthy aging simultaneously affects brain structure, brain function, and cognition. These
effects are often investigated in isolation ignoring any relationships between them. It is …

Older adults tend to over-activate regions throughout frontoparietal cortices and exhibit a
reduced range of functional modulation during WM task performance compared to younger …