Cell-free DNA (cfDNA) is a widely used noninvasive biomarker for diagnosis and prognosis
of multiple disease states. Emerging evidence suggests that cfDNA might not just be passive …

Cell-free DNA molecules are released into the plasma via apoptotic or necrotic events and
active release mechanisms, which carry the genetic and epigenetic information of its origin …

Epigenetic mechanisms play instrumental roles in gene regulation during embryonic
development and disease progression. However, it is challenging to non-invasively monitor …

Endogenous DNA is primarily found intracellularly in nuclei and mitochondria. However,
extracellular, cell-free (cf) DNA, has been observed in several pathological conditions …

Liquid biopsies can be used to analyse tissue-derived information, including cell-free DNA
(cfDNA), circulating rare cells, and circulating extracellular vesicles in the blood or other …

Cell-free DNA (cfDNA) as an emerging biomarker with huge potential for clinical application,
especially in the field of liquid biopsy. The field is now in a critical transitional period in which …

Recent advances in basic research have unveiled several strategies for improving the
sensitivity and specificity of cell-free DNA (cfDNA) based assays, which is a prerequisite for …

Cell-free DNA (cfDNA) is present in various body fluids and originates mostly from blood
cells. In specific conditions, circulating cfDNA might be derived from tumours, donor organs …

Cell-free DNA (cf. DNA) is a powerful noninvasive biomarker for cancer and prenatal testing,
and it circulates in plasma as short fragments. To elucidate the biology of cf. DNA …

Cell-free DNA (cfDNA) in bodily fluids has rapidly transformed the development of
noninvasive prenatal testing, cancer liquid biopsy, and transplantation monitoring. Plasma …