To defense harmful stimuli or maintain the immune homeostasis, the body produces and
recruits a superfamily of cytokines such as interleukins, interferons, chemokines etc. Among …

Chemokine is a structure-related protein with a relatively small molecular weight, which can
target cells to chemotaxis and promote inflammatory response. Inflammation plays an …

CCL13/MCP-4 belongs to the CC chemokine family, which induces chemotaxis in many
immune cells. Despite extensive research into its function in numerous disorders, a thorough …

The chemokine system mediates acute inflammation by driving leukocyte migration to
damaged or infected tissues. However, elevated expression of chemokines and their …

Chemokine receptor CCR6 is expressed on various cells such as B cells, immature dendritic
cells, innate lymphoid cells (ILCs), regulatory CD4 T cells, and Th17 cells. CCL20 is the only …

Introduction Chemokines and their cognate receptors play a major role in modulating
inflammatory responses. Depending on their ligand binding, chemokine receptors can …

CCR7, collaborated with its ligands CCL19 and CCL21, controls extensive migratory events
in the immune system. CCR7-bearing dendritic cells can swarm into T-cell zones in lymph …

Prototypical functions of the chemokine receptor CCR6 include immune regulation by
maneuvering cell chemotaxis and selective delimiting of the pro-inflammatory TH17 and …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is cause of the novel
coronavirus disease (COVID-19). In the last two years, SARS-CoV-2 has infected millions of …

Abstract CCL13/MCP-4, is a CC family chemokine that is chemoattractant for eosinophils,
basophils, monocytes, macrophages, immature dendritic cells, and T cells, and its capable …