Metabolomics in diabetic retinopathy: from potential biomarkers to molecular basis of oxidative stress

Q Jian, Y Wu, F Zhang - Cells, 2022 - mdpi.com
Diabetic retinopathy (DR), the leading cause of blindness in working-age adults, is one of
the most common complications of diabetes mellitus (DM) featured by metabolic disorders …

Metabolomics of various samples advancing biomarker discovery and pathogenesis elucidation for diabetic retinopathy

X Du, L Yang, L Kong, Y Sun, K Shen, Y Cai… - Frontiers in …, 2022 - frontiersin.org
Diabetic retinopathy (DR) is a universal microvascular complication of diabetes mellitus
(DM), which is the main reason for global sight damage/loss in middle-aged and/or older …

Multiplatform metabolomics reveals novel serum metabolite biomarkers in diabetic retinopathy subjects

Q Xuan, Y Ouyang, Y Wang, L Wu, H Li… - Advanced …, 2020 - Wiley Online Library
Diabetic retinopathy (DR) is the main cause of vision loss or blindness in working age adults
worldwide. The lack of effective diagnostic biomarkers for DR leads to unsatisfactory curative …

[HTML][HTML] Metabolomics in diabetic retinopathy: a systematic review

XW Hou, Y Wang, CW Pan - Investigative ophthalmology & …, 2021 - tvst.arvojournals.org
Purpose: Diabetic retinopathy (DR), a common microvascular complication of diabetes, is
the leading cause of acquired blindness in the working-age population. Individuals with …

Metabolomics of diabetic retinopathy

G Liew, Z Lei, G Tan, N Joachim, IV Ho, TY Wong… - Current diabetes …, 2017 - Springer
Abstract Purpose of Review Metabolomics is the study of dysregulated metabolites in
biological materials. We reviewed the use of the technique to elucidate the genetic and …

Metabolomics in retinal diseases: an update

X Li, S Cai, Z He, J Reilly, Z Zeng, N Strang, X Shu - Biology, 2021 - mdpi.com
Simple Summary Visual loss and blindness caused by retinal disease has a significant
negative effect on the quality of life of many adults and children, and as a result has become …

Metabolomics profiles associated with diabetic retinopathy in type 2 diabetes patients

JH Yun, JM Kim, HJ Jeon, T Oh, HJ Choi, BJ Kim - PLoS One, 2020 - journals.plos.org
Diabetic retinopathy (DR) is a common complication of diabetes, and it is the consequence
of microvascular retinal changes due to high glucose levels over a long time. Metabolomics …

Untargeted multiomics approach coupling lipidomics and metabolomics profiling reveals new insights in diabetic retinopathy

P Ancel, JC Martin, E Doukbi, M Houssays… - International Journal of …, 2023 - mdpi.com
Diabetic retinopathy (DR) is a microvascular complication of diabetes mellitus (DM) which is
the main cause of vision loss in the working-age population. Currently known risk factors …

Metabolomics window into diabetic complications

T Wu, S Qiao, C Shi, S Wang… - Journal of diabetes …, 2018 - Wiley Online Library
Diabetes has become a major global health problem. The elucidation of characteristic
metabolic alterations during the diabetic progression is critical for better understanding its …

Metabolites as risk factors for diabetic retinopathy in patients with type 2 diabetes: a 12-year follow-up study

L Fernandes Silva, J Hokkanen… - The Journal of …, 2024 - academic.oup.com
Context Diabetic retinopathy (DR) is a specific microvascular complication in patients with
diabetes and the leading cause of blindness. Recent advances in omics, especially …