Breast cancer is one of the most common malignant cancers among females worldwide.
This complex disease is not caused by a single gene, but resulted from multi-gene …

Breast cancer is one of the leading causes of mortality in females. A number of prognostic
markers have been identified, including single genes, multi‑gene signatures and network …

Breast cancer (BC) is a multifactorial disease and the most common cancer in women
worldwide. We describe a machine learning approach to identify a combination of …

Breast cancer is a complex cancer which includes many different subtypes. Identifying
prognostic modules, ie, functionally related gene networks that play crucial roles in cancer …

Breast cancer is one of the most prevalent cancers in females, with more than 450,000
deaths each year worldwide. Among the subtypes of breast cancer, basal-like breast cancer …

Ductal carcinoma in situ (DCIS) is a preinvasive form of breast cancer with a highly variable
potential of becoming invasive and affecting mortality of the patients. Due to the lack of …

Several prognostic signatures have been identified for breast cancer. However, these
signatures vary extensively in their gene compositions, and the poor concordance of the risk …

Although many methods have been proposed to reconstruct gene regulatory network, most
of them, when applied in the sample-based data, can not reveal the gene regulatory …

Background In a complex disease, the expression of many genes can be significantly
altered, leading to the appearance of a differentially expressed" disease module". Some of …

Background Recent discovery in tumor development indicates that the tumor
microenvironment (mostly stroma cells) plays an important role in cancer development. To …