Reperfusion is mandatory to salvage ischemic myocardium from infarction, but reperfusion
per se contributes to injury and ultimate infarct size. Therefore, cardioprotection beyond that …

Heart diseases due to myocardial ischemia, such as myocardial infarction or ischemic heart
failure, are major causes of death in developed countries, and their number is unfortunately …

Pre-, post-, and remote conditioning of the myocardium are well described adaptive
responses that markedly enhance the ability of the heart to withstand a prolonged …

Despite nearly twenty years of research into the field of ischemic preconditioning, the actual
mechanism of protection remains unclear. However, much progress has been made in …

Ischaemic postconditioning (brief periods of ischaemia alternating with brief periods of
reflow applied at the onset of reperfusion following sustained ischaemia) effectively reduces …

Several interventions, such as ischemic preconditioning, remote pre/perconditioning, or
postconditioning, are known to decrease lethal myocardial ischemia-reperfusion injury …

Adjunctive cardioprotective strategies for ameliorating the reversible and irreversible injuries
with ischemia-reperfusion (I/R) are highly desirable. However, after decades of research, the …

Coronary heart disease (CHD) is the leading cause of death globally. Following an acute
coronary artery occlusion, timely myocardial reperfusion using either primary percutaneous …

Coronary heart disease (CHD) is the leading cause of death world-wide. Its major
pathophysiological manifestation is acute myocardial ischaemia–reperfusion injury …

1075 Cardioprotection From IR Injury pathways and mitochondria modulation are implicated
in the cardioprotective effects of ischemic preconditioning (Figure 2). Nonlethal ischemia …