Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the
second most prevalent aortic disease following atherosclerosis, representing the ninth …

Background Aortic aneurysms (AA) are pathological dilations of the aorta, associated with
an overall mortality rate up to 90% in case of rupture. In addition to dilation, the aortic layers …

Aortic aneurysms are a common vascular disease in Western populations that can involve
virtually any portion of the aorta. Abdominal aortic aneurysms are much more common than …

Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease that affects,
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …

Abdominal aortic aneurysm (AAA) refers to the localized dilatation of the infra-renal aorta, in
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …

Objective—Recent studies suggested the occurrence of phenotypic switching of vascular
smooth muscle cells (VSMCs) during the development of aortic aneurysm (AA). However …

OBJECTIVES: Vascular smooth muscle cells can undergo profound changes in phenotype,
defined by coordinated repression of smooth muscle cell marker genes and production of …

The etiology of aortic aneurysms is poorly understood, but it is associated with
atherosclerosis, hypercholesterolemia, and abnormal transforming growth factor β (TGF-β) …

Aortic aneurysm is a chronic disease characterized by localized expansion of the aorta,
including the ascending aorta, arch, descending aorta, and abdominal aorta. Although aortic …

Objective: Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease
characterized by smooth muscle cell depletion, ECM (extracellular matrix) degradation, and …