Insulin resistance and sarcopenia: mechanistic links between common co-morbidities

ME Cleasby, P Jamieson, PJ Atherton - Journal of Endocrinology, 2016 - research.ed.ac.uk
Insulin resistance (IR) in skeletal muscle is a key defect mediating the link between obesity
and type 2 33 diabetes, a disease that typically affects people in later life. Sarcopenia (age …

[HTML][HTML] The impact of dysmetabolic sarcopenia among insulin sensitive tissues: a narrative review

A Armandi, C Rosso, GP Caviglia… - Frontiers in …, 2021 - frontiersin.org
Sarcopenia is a common muscular affection among elderly individuals. More recently, it has
been recognized as the skeletal muscle (SM) expression of the metabolic syndrome. The …

[HTML][HTML] Causal relationship between insulin resistance and sarcopenia

Z Liu, C Zhu - Diabetology & metabolic syndrome, 2023 - Springer
Sarcopenia is a multifactorial disease characterized by reduced muscle mass and function,
leading to disability, death, and other diseases. Recently, the prevalence of sarcopenia …

[HTML][HTML] Sarcopenia and diabetes: hyperglycemia is a risk factor for age-associated muscle mass and functional reduction

H Umegaki - Journal of diabetes investigation, 2015 - ncbi.nlm.nih.gov
Skeletal muscle maintains our posture and produces body movement. Muscle is essential to
make all movements required in daily life. Skeletal muscle has several other roles. It is a …

[HTML][HTML] Sarcopenia–endocrinological and neurological aspects

MK Stangl, W Böcker, V Chubanov… - Experimental and …, 2019 - thieme-connect.com
Sarcopenia in geriatric patients is often associated with or even caused by changes of the
endocrine and nervous system. The multifactorial pathogenesis of sarcopenia and …

[HTML][HTML] Health consequences of sarcopenic obesity: a narrative review

E Roh, KM Choi - Frontiers in endocrinology, 2020 - frontiersin.org
Sarcopenia is defined as the age-related loss of muscle mass and strength or physical
performance. Increased amounts of adipose tissue often accompany sarcopenia, a condition …

Sarcopenic obesity in older adults: aetiology, epidemiology and treatment strategies

JA Batsis, DT Villareal - Nature Reviews Endocrinology, 2018 - nature.com
The prevalence of obesity in combination with sarcopenia (the age-related loss of muscle
mass and strength or physical function) is increasing in adults aged 65 years and older. A …

Sarcopenia and type 2 diabetes mellitus: a bidirectional relationship

J Mesinovic, A Zengin, B De Courten… - … syndrome and obesity …, 2019 - Taylor & Francis
The incidence and prevalence of metabolic and musculoskeletal diseases are increasing.
Type 2 diabetes mellitus (T2DM) is characterized by insulin resistance, inflammation …

Sarcopenic obesity

SA Polyzos, AN Margioris - Hormones, 2018 - Springer
Sarcopenic obesity, a chronic condition, is today a major public health problem with
increasing prevalence worldwide, which is due to progressively aging populations, the …

Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review

C Li, K Yu, N Shyh‐Chang, Z Jiang… - Journal of cachexia …, 2022 - Wiley Online Library
Age‐associated obesity and muscle atrophy (sarcopenia) are intimately connected and are
reciprocally regulated by adipose tissue and skeletal muscle dysfunction. During ageing …