From a neurobiological perspective there is no such thing as bipolar disorder. Rather, it is
almost certainly the case that many somewhat similar, but subtly different, pathological …

Strakowski SM, Adler CM, Almeida J, Altshuler LL, Blumberg HP, Chang KD, DelBello MP,
Frangou S, McIntosh A, Phillips ML, Sussman JE, Townsend JD. The functional …

Aberrations in neurodevelopmental trajectories have been implicated in the neurobiology of
several mental disorders and evidence indicates a pathophysiological and genetic overlap …

This work provides an overview of the most consistent alterations in bipolar disorder (BD),
attempting to unify them in an internally coherent working model of the pathophysiology of …

The authors review existing structural and functional neuroimaging studies of patients with
bipolar disorder and discuss how these investigations enhance our understanding of the …

There is now strong evidence of progressive neuropathological processes in bipolar
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …

Bipolar disorder (BD) is a leading cause of global disability. Its biological basis is unknown,
and its treatment unsatisfactory. Here, we review two recent areas of progress. First, the …

The question of whether BD is primarily a developmental disorder or a progressive,
neurodegenerative disorder remains unresolved. Here, we review the morphometric …

Blond BN, Fredericks CA, Blumberg HP. Functional neuroanatomy of bipolar disorder:
structure, function, and connectivity in an amygdala–anterior paralimbic neural system …

Bipolar disorder (BPD) is a devastating illness that is characterized by recurrent episodes of
mania and depression. In addition to these cyclic episodes, individuals with BPD exhibit …