Homogeneity and heterogeneity of the cytopathological mechanisms in different etiology-
induced acute kidney injury (AKI) are poorly understood. Here, we performed single-cell …

Background Understanding the acute kidney injury (AKI) microenvironment changes and the
complex cellular interaction is essential to elucidate the mechanisms and develop new …

Acute kidney injury (AKI), commonly caused by ischemia, sepsis, or nephrotoxic insult, is
associated with increased mortality and a heightened risk of chronic kidney disease (CKD) …

Acute kidney injury (AKI) is an important risk factor for chronic kidney disease (CKD), but the
underlying mechanisms of failed tubule repair and AKI-CKD transition are incompletely …

Background Current management of AKI, a potentially fatal disorder that can also initiate or
exacerbate CKD, is merely supportive. Therefore, deeper understanding of the molecular …

Acute kidney injury (AKI) is a syndrome of reduced glomerular filtration rate and urine
production caused by a number of different diseases. It is associated with renal tissue …

Acute kidney injury (AKI) is a common clinical condition associated with high morbidity and
mortality. The pathogenesis of AKI has not been fully elucidated, with a lack of effective …

Acute kidney injury (AKI) induces a broad range of clinically significant perturbations in
kidney morphology and function. Insights into the molecular and cellular basis governing a …

Acute kidney injury (AKI) currently is diagnosed by a temporal trend of a single blood
analyte: serum creatinine. This measurement is neither sensitive nor specific to kidney injury …

Acute kidney injury (AKI) is a major risk factor for long-term adverse outcomes, including
chronic kidney disease. In mouse models of AKI, maladaptive repair of the injured proximal …