Comparison of senescence-related changes between three-and two-dimensional cultured adipose-derived mesenchymal stem cells

Q Yin, N Xu, D Xu, M Dong, X Shi, Y Wang… - Stem Cell Research & …, 2020 - Springer
Background Adipose-derived mesenchymal stem cells (ADMSCs) have attracted
widespread interest as cell-based tissue repair systems. To obtain adequate quantities of …

Characterization of senescence of human adipose-derived stem cells after long-term expansion

NC Truong, KHT Bui, P Van Pham - Tissue engineering and regenerative …, 2019 - Springer
Introduction: Since the 1980s, adipose-derived stem cells (ASCs) have become a powerful
and potential source for stem cell-based therapy, regenerative medicine, and even drug …

[HTML][HTML] Isolation, culturing, characterization and aging of adipose tissue-derived mesenchymal stem cells: a brief overview

E Fathi, R Farahzadi - Brazilian Archives of Biology and Technology, 2016 - SciELO Brasil
The aim of this review was to describe the current state-of-the-art regarding isolation,
characterization and aging of adipose tissue-derived mesenchymal stem cells (ADSCs) …

Methods and strategies for procurement, isolation, characterization, and assessment of senescence of human mesenchymal stem cells from adipose tissue

M Gaur, M Dobke, VV Lunyak - Stem Cells and Aging: Methods and …, 2019 - Springer
Human adipose-derived mesenchymal stem (stromal) cells (hADSC) represent an attractive
source of the cells for numerous therapeutic applications in regenerative medicine. These …

Donor age negatively impacts adipose tissue-derived mesenchymal stem cell expansion and differentiation

MS Choudhery, M Badowski, A Muise, J Pierce… - Journal of translational …, 2014 - Springer
Background Human adipose tissue is an ideal autologous source of mesenchymal stem
cells (MSCs) for various regenerative medicine and tissue engineering strategies. Aged …

[HTML][HTML] Enhancement of individual differences in proliferation and differentiation potentials of aged human adipose-derived stem cells

M Kawagishi-Hotta, S Hasegawa, T Igarashi… - Regenerative …, 2017 - Elsevier
Background Adipose-derived stem cells (ASCs) are a robust, multipotent cell source. They
are easily obtained and hold promise in many regenerative applications. It is generally …

Human adipose‐derived stem cells exhibit enhanced proliferative capacity and retain multipotency longer than donor‐matched bone marrow mesenchymal stem cells …

KL Burrow, JA Hoyland… - Stem cells …, 2017 - Wiley Online Library
Bone marrow‐derived mesenchymal stem cells (MSCs) and adipose‐derived multipotent/
mesenchymal stem cells (ASCs) have been proposed as the ideal cell types for a range of …

[HTML][HTML] Characterization of senescence of culture-expanded human adipose-derived mesenchymal stem cells

D Legzdina, A Romanauska… - … journal of stem …, 2016 - synapse.koreamed.org
Methods and Results ADSC cultures from 8 donors were cultivated until proliferation arrest
was reached. A gradual decline of ADSC fitness was observed by altered cell morphology …

Adipose-derived mesenchymal stem cells from the elderly exhibit decreased migration and differentiation abilities with senescent properties

M Liu, H Lei, P Dong, X Fu, Z Yang, Y Yang… - Cell …, 2017 - journals.sagepub.com
Adipose-derived stem cells (ASCs) can be applied extensively in the clinic because they can
be easily isolated and cause less donor-site morbidity; however, their application can be …

The impact of long-term in vitro expansion on the senescence-associated markers of human adipose-derived stem cells

WKZW Safwani, S Makpol, S Sathapan… - Applied biochemistry and …, 2012 - Springer
Human adipose-derived stem cells (ASCs) have generated a great deal of excitement in
regenerative medicine. However, their safety and efficacy issue remain a major concern …