J Li, K Zhang, ye Zhang, Z Gu, C Huang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to acute …
M Pastorek, M Dúbrava, P Celec - Frontiers in Immunology, 2022 - frontiersin.org
Despite ongoing vaccination COVID-19 is a global healthcare problem because of the lack of an effective targeted therapy. In severe COVID-19 manifesting as acute respiratory …
SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs, occasionally causing death. Until effective vaccines are developed to curb the pandemic, it …
The COVID-19 pandemic is progressing worldwide with an alarming death toll. There is an urgent need for novel therapeutic strategies to combat potentially fatal complications …
Background Increased inflammation has been well defined in coronavirus disease 2019 (COVID-19), while definitive pathways driving severe forms of this disease remain uncertain …
The SARS-Cov2 infection triggers a multisystem inflammatory disorder, knowing as COVID- 19, a pandemic disease. This disease is characterized by acute respiratory distress …
E McKenna, R Wubben, JM Isaza-Correa… - Frontiers in …, 2022 - frontiersin.org
Unusually for a viral infection, the immunological phenotype of severe COVID-19 is characterised by a depleted lymphocyte and elevated neutrophil count, with the neutrophil …
The novel coronavirus SARS-CoV-2 causes COVID-19, a highly pathogenic viral infection threatening millions. The majority of the individuals infected are asymptomatic or mildly …
FP Veras, MC Pontelli, CM Silva… - Journal of Experimental …, 2020 - rupress.org
Severe COVID-19 patients develop acute respiratory distress syndrome that may progress to cytokine storm syndrome, organ dysfunction, and death. Considering that neutrophil …