The brain is supplied by an elaborate vascular network that originates extracranially and
reaches deep into the brain. The concept of the neurovascular unit provides a useful …

At first sight, the nervous and vascular systems seem to share little in common. However,
neural and vascular cells not only are anatomically closely tied to each other, but they also …

Historically, the neuron has been the conceptual focus for almost all of neuroscience
research. In recent years, however, the concept of the neurovascular unit has emerged as a …

The mammalian brain is supplied with blood by specialized vasculature that is structurally
and functionally distinct from that of the periphery. A defining feature of this vasculature is a …

Molecular cross talk between the nervous and vascular systems is necessary to maintain the
correct coupling of organ structure and function. Molecular pathways shared by both …

The cerebrovasculature is essential to brain health and is tasked with ensuring adequate
delivery of oxygen and metabolic precursors to ensure normal neurologic function. This is …

Purpose of the review: The synchronic development of vascular and nervous systems is
orchestrated by common molecules that regulate the communication between both systems …

The human central nervous system (CNS) features a network of∼ 400 miles of blood
vessels that receives> 20% of the body's cardiac output and uses most of its blood glucose …

The CNS critically relies on the formation and proper function of its vasculature during
development, adult homeostasis and disease. Angiogenesis—the formation of new blood …

Endothelial cells (ECs) build blood vessels and regulate their plasticity in coordination with
neurons. Likewise, neurons construct nerves and regulate their circuits in coordination with …