Exome sequencing to explore the possibility of predicting genetic susceptibility to the joint occurrence of polycystic ovary syndrome and Hashimoto's thyroiditis

N Zeber-Lubecka, K Suchta, M Kulecka… - Frontiers in …, 2023 - frontiersin.org
A large body of evidence indicates that women with polycystic ovary syndrome (PCOS) have
a higher risk of developing Hashimoto's thyroiditis (HT) than healthy individuals. Given the …

Genetic susceptibility to joint occurrence of polycystic ovary syndrome and Hashimoto's thyroiditis: how far is our understanding?

N Zeber-Lubecka, EE Hennig - Frontiers in immunology, 2021 - frontiersin.org
Polycystic ovary syndrome (PCOS) and Hashimoto's thyroiditis (HT) are endocrine disorders
that commonly occur among young women. A higher prevalence of HT in women with …

Thyroid function and polycystic ovary syndrome: a Mendelian randomization study

Z Zhao, Y Gao, X Pei, W Wang, R Wang… - Frontiers in …, 2024 - frontiersin.org
Background Multiple evidence suggests that thyroid function is associated with polycystic
ovary syndrome (PCOS), but whether thyroid function is causally related to PCOS is unclear …

Genome-wide association analysis suggests novel loci for Hashimoto's thyroiditis

L Brčić, A Barić, S Gračan, M Brekalo… - Journal of …, 2019 - Springer
Purpose Hashimoto's thyroiditis (HT) is the most common form of autoimmune thyroid
diseases. Current knowledge of HT genetics is limited, and not a single genome-wide …

Correlation between Hashimoto's thyroiditis and polycystic ovary syndrome: A systematic review and meta-analysis

X Hu, Y Chen, Y Shen, S Zhou, W Fei… - Frontiers in …, 2022 - frontiersin.org
Objective A growing body of research suggests that patients with polycystic ovary syndrome
(PCOS) may be at increased risk of developing Hashimoto's thyroiditis (HT), and having both …

[PDF][PDF] Thyroid disorders in polycystic ovary syndrome.

K Kowalczyk, G Franik, D Kowalczyk… - European Review for …, 2017 - researchgate.net
OBJECTIVE: Thyroid disorders, especially Hashimoto's thyroiditis (HT), are observed
significantly more often in patients with polycystic ovary syndrome (PCOS) than in the …

Is thyroid function associated with polycystic ovary syndrome? A bidirectional Mendelian randomization study

Q Zhang, W Ke, J Ye, P Zhang, Q Yang, F Pan, K Wang… - Endocrine, 2024 - Springer
Objective Some observational studies have suggested the association between thyroid
function and polycystic ovary syndrome (PCOS). However, it remains to be determined …

A polygenic and phenotypic risk prediction for polycystic ovary syndrome evaluated by phenome-wide association studies

YY Joo, KE Actkins, JA Pacheco… - The Journal of …, 2020 - academic.oup.com
Context As many as 75% of patients with polycystic ovary syndrome (PCOS) are estimated
to be unidentified in clinical practice. Objective Utilizing polygenic risk prediction, we aim to …

Genome-wide association analysis suggests novel loci underlying thyroid antibodies in Hashimoto's thyroiditis

L Brčić, A Barić, S Gračan, V Torlak, M Brekalo… - Scientific reports, 2019 - nature.com
Thyroid antibodies against thyroglobulin (TgAb) and thyroid peroxidase (TPOAb) are key
markers of Hashimoto's thyroiditis (HT), the most common autoimmune thyroid disorder …

Identifying and analyzing the key genes shared by papillary thyroid carcinoma and Hashimoto's thyroiditis using bioinformatics methods

T Liu, D Yin, N Wang, N Li, G Dong… - Frontiers in …, 2023 - frontiersin.org
Background Hashimoto's thyroiditis (HT) is a chronic autoimmune disease that poses a risk
factor for papillary thyroid carcinoma (PTC). The present study aimed to identify the key …