[HTML][HTML] Protective effects of curcumin against traumatic brain injury

D Khayatan, SM Razavi, ZN Arab, AH Niknejad… - Biomedicine & …, 2022 - Elsevier
Neuroinflammation is a key pathophysiological mechanism implicated in the
neurodegenerative condition. One such condition implicating neuroinflammation is traumatic …

Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway in experimental traumatic brain injury

H Zhu, C Bian, J Yuan, W Chu, X Xiang, F Chen… - Journal of …, 2014 - Springer
Background Traumatic brain injury (TBI) initiates a neuroinflammatory cascade that
contributes to substantial neuronal damage and behavioral impairment, and Toll-like …

Neuroprotective effects of curcumin in cerebral ischemia: cellular and molecular mechanisms

L Subedi, BP Gaire - ACS Chemical Neuroscience, 2021 - ACS Publications
Despite being a major global health concern, cerebral ischemia/stroke has limited
therapeutic options. Tissue plasminogen activator (tPA) is the only available medication to …

Protective effects of curcumin against ischemia-reperfusion injury in the nervous system

K Bavarsad, GE Barreto, MAR Hadjzadeh… - Molecular …, 2019 - Springer
Ischemia-reperfusion injury (I/R injury) is a common feature of ischemic stroke which occurs
when blood supply is restored after a period of ischemia. Although stroke is an important …

The clinical use of curcumin on neurological disorders: An updated systematic review of clinical trials

M Mohseni, A Sahebkar, G Askari… - Phytotherapy …, 2021 - Wiley Online Library
Neuroprotective effects of curcumin have been shown in previous studies. This updated
systematic review of clinical trials aimed to investigate the effect of curcumin on neurological …

Therapeutic potential of curcumin for multiple sclerosis

M Qureshi, EA Al-Suhaimi, F Wahid, O Shehzad… - Neurological …, 2018 - Springer
Multiple sclerosis (MS) is a chronic autoimmune inflammatory disease of the central nervous
system (CNS), characterized by demyelination, neuronal injury, and breaching of the blood …

Curcumin provides neuroprotection in model of traumatic brain injury via the Nrf2-ARE signaling pathway

W Dai, H Wang, J Fang, Y Zhu, J Zhou, X Wang… - Brain research …, 2018 - Elsevier
Curcumin has been found to play the protective role in many neurological disorders,
however, its roles and the underlying molecular mechanisms in traumatic brain injury (TBI) …

New promising therapeutic avenues of curcumin in brain diseases

T Benameur, G Giacomucci, MA Panaro, M Ruggiero… - Molecules, 2021 - mdpi.com
Curcumin, the dietary polyphenol isolated from Curcuma longa (turmeric), is commonly used
as an herb and spice worldwide. Because of its bio-pharmacological effects curcumin is also …

Curcumin prevents reperfusion injury following ischemic stroke in rats via inhibition of NF‑κB, ICAM-1, MMP-9 and caspase-3 expression

W Li, NC Suwanwela… - Molecular medicine …, 2017 - spandidos-publications.com
Reperfusion is the only approved therapy for acute ischemic stroke; however, it can cause
excessive inflammation responses and aggravate brain damage. Therefore, supplementary …

Benefits of curcumin in brain disorders

A Bhat, AM Mahalakshmi, B Ray, S Tuladhar… - …, 2019 - Wiley Online Library
Curcumin is widely consumed in Asia either as turmeric directly or as one of the culinary
ingredients in food recipes. The benefits of curcumin in different organ systems have been …