Background This study was to explore the infiltration pattern of immune cells in the prostate
cancer (PCa) microenvironment and evaluate the possibility of specific infiltrating immune …

Background The tumor microenvironment (TME) primarily comprises cancer cells, cancer-
infiltrating immune cells, and stromal cells. The tumor cells alter the TME by secreting …

Immune microenvironment of prostate cancer (PCa) is implicated in disease progression.
However, previous studies have not fully explored PCa immune microenvironment. This …

Prostate cancer (PCa), a severe health burden for males, accounts for the second frequent
cancer and fifth tumor specific death cancer around the world. Several studies on tumor …

Improved risk stratification is needed for patients with localized prostate cancer. This study
characterized and assessed the prognostic potential of distinct immune cell infiltration …

BACKGROUNDS The adaptive immune system can potentially have dual roles in cancer
development and progression by contributing to or suppressing tumor progression and …

Androgen deprivation therapy (ADT) is a cornerstone treatment for locally advanced or
metastatic prostate cancer (PCa). However, its potential effects on the tumor immune …

Background Some historic breakthroughs have been made in immunotherapy of advanced
cancer. However, there is still little research on immunotherapy in prostate cancer. We …

Prostate cancer (PCa) is one of the most common malignancies in male. We aim to establish
a novel gene signature for immune infiltration and outcome (biochemical recurrence (BCR) …

Dear Editor, Prostate cancer (PCa) is traditionally considered an immunologically cold
tumour characterized by an immunosuppressive tumour microenvironment (TME) and a …