Trillin-Mediated Inhibition of NF-κB/COX-2 Signaling Pathways through Upregulation of miR-145-5p Targeting MAP3K11 in Castration-Resistant Prostate Cancer
Y Wang, Y Peng, W Hao, X Gao, P Liang, H Zhao… - 2024 - researchsquare.com
Purpose Prostate cancer remains a leading cause of cancer-related deaths among men
worldwide, driving the need for innovative therapeutic avenues. Despite preliminary …
worldwide, driving the need for innovative therapeutic avenues. Despite preliminary …
Trillin Inhibit NF-κB/COX-2/MAPK Signaling Pathways Through Upregulation of miR-145-5p in Castration-Resistant Prostate Cancer
Y Wang, Y Peng, W Hao, X Gao, P Liang, H Zhao… - papers.ssrn.com
Prostate cancer is a common malignancy in men, which transforms into castration-resistant
prostate cancer (CRPC) after androgen deprivation therapy (ADT). However, the optimal …
prostate cancer (CRPC) after androgen deprivation therapy (ADT). However, the optimal …
Veratramine Inhibits the Cell Cycle Progression, Migration, and Invasion via ATM/ATR Pathway in Androgen-Independent Prostate Cancer
HY Kim, SW Lee, SK Choi, J Ashim, W Kim… - The American Journal …, 2023 - World Scientific
Prostate cancer (PC) is the second leading cause of cancer-related death among men.
Treatment of PC becomes difficult after progression because PC that used to be androgen …
Treatment of PC becomes difficult after progression because PC that used to be androgen …
[HTML][HTML] MiR-4638-5p inhibits castration resistance of prostate cancer through repressing Kidins220 expression and PI3K/AKT pathway activity
Y Wang, N Shao, X Mao, M Zhu, W Fan, Z Shen… - Oncotarget, 2016 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are short, conserved segments of non-coding RNA which play a
significant role in prostate cancer development and progression. To identify miRNAs …
significant role in prostate cancer development and progression. To identify miRNAs …
[HTML][HTML] Concurrent treatment with simvastatin and NF-κB inhibitor in human castration-resistant prostate cancer cells exerts synergistic anti-cancer effects via control …
M Kang, KH Lee, HS Lee, CW Jeong, JH Ku, HH Kim… - PLoS …, 2017 - journals.plos.org
We examined the anti-cancer effects and molecular mechanism of simvastatin in human
castration-resistant prostate cancer (CRPC) cells, particularly focused on LIN28B and its …
castration-resistant prostate cancer (CRPC) cells, particularly focused on LIN28B and its …
[HTML][HTML] BK002 Induces miR-192-5p-Mediated Apoptosis in Castration-Resistant Prostate Cancer Cells via Modulation of PI3K/CHOP
BK002 consists of Achyranthes japonica Nakai (AJN) and Melandrium firmum Rohrbach
(MFR) that have been used as herbal medicines in China and Korea. AJN and MFR have …
(MFR) that have been used as herbal medicines in China and Korea. AJN and MFR have …
Modulating the PI3K/AKT/mTOR Signaling Pathway with Novel Compounds to Improve Treatment of Castration-Resistant Prostate Cancer
Y Zaidi - jmsgr.tamhsc.edu
Background: Prostate cancer is a major global health concern. 1 Castration-resistant
prostate cancer (CRPC) is an advanced subtype that poses a significant challenge due to its …
prostate cancer (CRPC) is an advanced subtype that poses a significant challenge due to its …
[HTML][HTML] Targeting TR4 nuclear receptor with antagonist bexarotene increases docetaxel sensitivity to better suppress the metastatic castration-resistant prostate …
L Hu, Y Sun, J Luo, X He, M Ye, G Li, Y Zhang, J Bai… - Oncogene, 2020 - nature.com
Prostate cancer (PCa) is the second leading cause of cancer death in men in America, and
there are no curative options for metastatic castration-resistant prostate cancer (mCRPC) …
there are no curative options for metastatic castration-resistant prostate cancer (mCRPC) …
[HTML][HTML] In vitro and in vivo anticancer activity of Lycorine in prostate cancer by inhibiting NF-κB signaling pathway
J Liu, S Sun, C Zhou, Z Sun, Q Wang, C Sun - Journal of Cancer, 2022 - ncbi.nlm.nih.gov
NF-κB transcription factors critically regulate the expression of genes which are involved in
important cellular processes, including cellular proliferation and apoptosis. Abnormal …
important cellular processes, including cellular proliferation and apoptosis. Abnormal …
[HTML][HTML] Silencing of LINC01963 enhances the chemosensitivity of prostate cancer cells to docetaxel by targeting the miR-216b-5p/TrkB axis
Z Xing, S Li, J Xing, G Yu, G Wang, Z Liu - Laboratory investigation, 2022 - Elsevier
Docetaxel (DTX) treatment effectively prolongs the overall survival of patients with prostate
cancer. However, most patients eventually develop resistance to chemotherapy and …
cancer. However, most patients eventually develop resistance to chemotherapy and …