Background Personalised medicine is a medical model that aims to provide tailor-made
prevention and treatment strategies for defined groups of individuals. The concept brings …

Objective Personalised medicine (PM) allows treating patients based on their individual
demographic, genomic or biological characteristics for tailoring the 'right treatment for the …

Background The development of personalised (stratified) medicine is intrinsically dependent
on an understanding of treatment-effect mechanisms (effects on therapeutic targets that …

The introduction of personalized medicine, through the increasing multi-omics
characterization of disease, brings new challenges to disease modeling. The scope of this …

Inspired by a hugely successful series entitled Treating Individuals, originally published in
The Lancet, this volume will become essential reading for any professional involved with …

The potential benefits that preventive, predictive and personalised medicine approaches
can bring to healthcare are discussed with much interest throughout the EU. This novel …

Background Classically, randomised controlled trials (RCTs) are considered the gold
standard for demonstrating product efficacy for the regulatory approval of medicines …

Background: personalised health care has been claimed to play an outstanding role in the
future health services. In fact, health care systems will have to face changes in their work …

Objectives This study aimed to review the degree of personalization of benefit and harm in
the reporting of recent high-profile randomized controlled trials (RCTs) involving …

Introduction Classic randomized controlled trial design provides information about the
effectiveness of a treatment at population level. In clinical practice based on precision …