Locally advanced pancreatic cancer (LAPC) has several definitions but essentially is a
nonmetastasized pancreatic cancer, in which upfront resection is considered not beneficial …

Pancreatic cancer is an aggressive cancer that continues to have single-digit 5-year
mortality rates despite advancements in the field. Surgery remains the only curative …

Background Patients with locally advanced pancreatic cancer have historically been
considered inoperable. The purpose of this report was to determine resectability rates for …

Background Locally advanced unresectable pancreatic cancer (LAPC) historically portends
a poor prognosis. FOLFIRINOX and gemcitabine/nab-paclitaxel have proven effective in the …

Due to differences in natural history and therapy, clinical trials of patients with advanced
pancreatic cancer have recently been subdivided into unresectable locally advanced …

Abstract Purpose of Review Pancreatic ductal adenocarcinoma (PDAC) is one of the most
aggressive neoplasms, bearing a terrible prognosis. Stage III tumors, also known as locally …

Almost 30% of patients with pancreatic cancer present with large, locally advanced tumors in
the absence of distant metastases. Because surgical resection is frequently contraindicated …

Introduction Since current studies on locally advanced pancreatic cancer (LAPC) mainly
report from single, high-volume centers, it is unclear if outcomes can be translated to daily …

Background and Objectives Though necessary for improved outcomes, surgical resection is
often limited in patients with locally advanced pancreatic cancers (LAPCs). We evaluated …

Pancreatic ductal adenocarcinoma is a highly lethal cancer that is rarely curable at the time
of presentation. Unfortunately, most patients are diagnosed with either metastatic or locally …