Introduction: The gastrointestinal mucosa constitutes a critical barrier where millions of
microbes and environmental antigens come in close contact with the host immune system …

The intestinal mucosa provides a selective permeable barrier for nutrient absorption and
protection from external factors. It consists of epithelial cells, immune cells and their …

OBJECTIVE: Gut barrier is a functional unit organized as a multi-layer system and its
multiple functions are crucial for maintaining gut homeostasis. Numerous scientific …

The gastrointestinal mucosal surface is lined with epithelial cells representing an effective
barrier made up with intercellular junctions that separate the inner and the outer …

A fundamental function of the intestinal epithelium is to act as a barrier that limits interactions
between luminal contents such as the intestinal microbiota, the underlying immune system …

The gastrointestinal tract is a specialized organ in which dynamic interactions between host
cells and the complex environment occur in addition to food digestion. Together with the …

The intestine constitutes the largest interface between a person and his or her environment,
and an intact intestinal barrier is thus essential in maintaining health and preventing tissue …

The objectives of this review on 'leaky gut'for clinicians are to discuss the components of the
intestinal barrier, the diverse measurements of intestinal permeability, their perturbation in …

A reduction in intestinal barrier function is currently believed to play an important role in
pathogenesis of many diseases, as it facilitates passage of injurious factors such as …

Data are accumulating that emphasize the important role of the intestinal barrier and
intestinal permeability for health and disease. However, these terms are poorly defined, their …