Brain-predicted age difference score is related to specific cognitive functions: a multi-site replication analysis

R Boyle, L Jollans, LM Rueda-Delgado, R Rizzo… - Brain imaging and …, 2021 - Springer
Brain-predicted age difference scores are calculated by subtracting chronological age from
'brain'age, which is estimated using neuroimaging data. Positive scores reflect accelerated …

Predicting brain age with deep learning from raw imaging data results in a reliable and heritable biomarker

JH Cole, RPK Poudel, D Tsagkrasoulis, MWA Caan… - NeuroImage, 2017 - Elsevier
Abstract Machine learning analysis of neuroimaging data can accurately predict
chronological age in healthy people. Deviations from healthy brain ageing have been …

Brain-predicted age difference is associated with cognitive processing in later-life

J Wrigglesworth, N Yaacob, P Ward, RL Woods… - Neurobiology of …, 2022 - Elsevier
Brain age is a neuroimaging-based biomarker of aging. This study examined whether the
difference between brain age and chronological age (brain-PAD) is associated with …

[HTML][HTML] Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study

AMG De Lange, M Anatürk, S Suri, T Kaufmann… - NeuroImage, 2020 - Elsevier
Brain age is becoming a widely applied imaging-based biomarker of neural aging and
potential proxy for brain integrity and health. We estimated multimodal and modality-specific …

Brain age prediction across the human lifespan using multimodal MRI data

S Guan, R Jiang, C Meng, B Biswal - GeroScience, 2024 - Springer
Measuring differences between an individual's age and biological age with biological
information from the brain have the potential to provide biomarkers of clinically relevant …

[HTML][HTML] Multimodality neuroimaging brain-age in UK biobank: relationship to biomedical, lifestyle, and cognitive factors

JH Cole - Neurobiology of aging, 2020 - Elsevier
The brain-age paradigm is proving increasingly useful for exploring aging-related disease
and can predict important future health outcomes. Most brain-age research uses structural …

[HTML][HTML] Estimation of brain age delta from brain imaging

SM Smith, D Vidaurre, F Alfaro-Almagro, TE Nichols… - Neuroimage, 2019 - Elsevier
It is of increasing interest to study “brain age”-the apparent age of a subject, as inferred from
brain imaging data. The difference between brain age and actual age (the “delta”) is typically …

Prediction of brain age and cognitive age: Quantifying brain and cognitive maintenance in aging

M Anatürk, T Kaufmann, JH Cole, S Suri… - Human brain …, 2021 - Wiley Online Library
The concept of brain maintenance refers to the preservation of brain integrity in older age,
while cognitive reserve refers to the capacity to maintain cognition in the presence of …

Linking brain age gap to mental and physical health in the Berlin aging study II

P Jawinski, S Markett, J Drewelies, S Düzel… - Frontiers in Aging …, 2022 - frontiersin.org
From a biological perspective, humans differ in the speed they age, and this may manifest in
both mental and physical health disparities. The discrepancy between an individual's …

[HTML][HTML] Estimating brain age from structural MRI and MEG data: Insights from dimensionality reduction techniques

A Xifra-Porxas, A Ghosh, GD Mitsis, MH Boudrias - NeuroImage, 2021 - Elsevier
Brain age prediction studies aim at reliably estimating the difference between the
chronological age of an individual and their predicted age based on neuroimaging data …