IL-6 level but not MBL level is associated with disease severity in hospitalized patients with COVID-19

Y Söyler, P Akın Kabalak, D Kızılgöz… - Eurasian Journal …, 2023 - eurasianjpulmonol.com
BACKGROUND AND AIM: The identification of reliable biomarkers for severe Coronavirus
Disease 2019 (COVID-19) is still needed. Therefore, we analyzed mannose-binding lectin …

The soluble lectin families as novel biomarkers for COVID-19 pneumonia

H Takenaka, A Saito, K Kuronuma, K Moniwa… - in vivo, 2023 - iv.iiarjournals.org
Background/Aim: The lung-specific soluble lectins, SP-A and SP-D have been clinically
used to diagnose interstitial lung disease, but their clinical significance in COVID-19 remains …

[PDF][PDF] The relationship between COVID-19 and the complement system: mannose-binding lectin.

DE Afşin, A Aksakal, AF Kilic… - European Review for …, 2023 - europeanreview.org
OBJECTIVE: Mannose-binding lectin (MBL) is one of the important parts of the complement
system. In our study, we aimed to determine serum MBL levels and their relationship with …

Interleukin-6 and C-reactive protein/albumin ratio as predictors of COVID-19 severity and mortality

M El-Shabrawy, ME Alsadik, M El-Shafei… - The Egyptian Journal of …, 2021 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) was announced in early
December 2019. The pandemic situation is declared. This study aimed to evaluate the role …

High production MBL2 polymorphisms protect against COVID-19 complications in critically ill patients: A retrospective cohort study

LV de Andrade, MV de Souza Sá, B Vasconcelos… - Heliyon, 2024 - cell.com
Mannose-binding lectin (MBL) binds to SARS-CoV-2, inhibits infection of susceptible cells,
and activates the complement system via the lectin pathway. In this study, we investigated …

The role of the lectin pathway of the complement system in SARS-CoV-2 lung injury

MAS Malaquias, AC Gadotti… - Translational …, 2021 - Elsevier
Although some evidence showed the activation of complement systems in COVID-19
patients, proinflammatory status and lectin pathway remain unclear. Thus, the present study …

Polymorphisms in the MBL2 gene are associated with the plasma levels of MBL and the cytokines IL-6 and TNF-α in severe COVID-19

MAF Queiroz, AM Santiago, WRS Brito… - Frontiers in …, 2023 - frontiersin.org
Introduction Mannose-binding lectin (MBL) promotes opsonization, favoring phagocytosis
and activation of the complement system in response to different microorganisms, and may …

Differences in IL-6 Levels Based on Clinical Severity and Outcome of COVID-19 Patients at Dr. M. Djamil Hospital

CW Morfi, YS Sabri, D Mizarti - Respiratory Science, 2023 - respiratoryscience.or.id
Abstract ground: A cytokine storm is defined by elevated levels of proinflammatory cytokines
such as interleukin-6 (IL-6). In COVID-19 infection, IL-6 is superior to C-reactive protein …

The MBL2 genotype relates to COVID-19 severity and may help to select the optimal therapy

F Scialò, G Cernera, S Esposito, B Pinchera… - Clinical Chemistry and …, 2023 - degruyter.com
Abstract Objectives Sars-CoV-2 acute infection is clinically heterogeneous, ranging from
asymptomatic cases to patients with a severe, systemic clinical course. Among the involved …

[HTML][HTML] The role of IL-6/lymphocyte ratio in the peripheral blood of severe patients with COVID-19

B Yang, X Chang, J Huang, W Pan, Z Si… - International …, 2021 - Elsevier
Background To investigate the prognostic value of a novel immune-inflammatory index, the
interleukin-6-to-lymphocyte ratio (IL-6/LY), with the clinical outcomes of severe coronavirus …