On average, most aspects of adult human brains and cognitive functions experience decline
with age, yet individuals also differ greatly in how much decline they experience. This review …

" Provides a unique perspective. I am particularly impressed with the sections on innovative
design and methods to investigate cognitive aging and the integrative perspectives. None of …

With dementia incidence projected to escalate significantly within the next 25 years, the
United Nations declared 2021-2030 the Decade of Healthy Ageing, emphasising cognition …

The past 25 years have provided a rich discovery of at least four fundamental patterns that
represent structural and functional brain aging across multiple cognitive domains. Of the …

Age-related cognitive declines are common and inevitable, but life trajectories of brain and
cognitive functions are variable and plastic. To identify the mechanisms of decline, the …

Declining cognitive functions are a normal and inevitable part of healthy aging. Some
changes may stem from global alterations in brain functions, including metabolic changes; …

Normal cognitive and brain aging are a set of interconnected and complex biological
phenomena that can be understood from a multidisciplinary and integrative approach …

Cognitive aging is often described in the context of loss or decline. Emerging research
suggests that the story is more complex, with older adults showing both losses and gains in …

The underlying premise of current theories of cognitive decline with age tend to be primarily
cognitive or biological explanations, with relatively few theories adequately integrating both …

Aging in the absence of neurodegenerative disease is frequently accompanied by deficits in
memory and other cognitive capacities. Although relatively modest in severity, these …