Lactobacillus plantarum mitigates sexual-reproductive deficits by modulating insulin receptor expression in the hypothalamic-pituitary-testicular axis of …

EE Edem, BU Nathaniel, KE Nebo… - Drug Metabolism and …, 2021 - degruyter.com
Objectives Hyperinsulinemia increases the risk factor of diabetes and infertility at a manifold.
Lactobacillus plantarum has several medical significances with limited reports. Hence, this …

The potential therapeutic effects of Lactobacillus plantarum and inulin on serum and testicular reproductive markers in diabetic male rats

M Rahimiyan-Heravan, L Roshangar, P Karimi… - Diabetology & Metabolic …, 2020 - Springer
Background It is well established that diminished reproductive health is one of the notable
long-term outcomes of type 2 diabetes mellitus (T2DM), especially among males. Due to the …

Protective effects of Lycium barbarum polysaccharide on male sexual dysfunction and fertility impairments by activating hypothalamic pituitary gonadal axis in …

GJ Shi, J Zheng, J Wu, HQ Qiao, Q Chang, Y Niu… - Endocrine …, 2017 - jstage.jst.go.jp
Diabetes-associated male sexual dysfunction and fertility impairments are both common
clinical complications with limited therapeutic options; hence it seriously affects the quality of …

Effects of Lycium barbarum Polysaccharide on Endoplasmic Reticulum Stress and Oxidative Stress in Obese Mice

FL Yang, YX Wei, BY Liao, GJ Wei, HM Qin… - Frontiers in …, 2020 - frontiersin.org
Background The incidence of obesity-associated decline in male fertility has increased over
the years. Lycium barbarum polysaccharide (LBP), a natural plant polysaccharide extracted …

A Synbiotic Combination of Lactobacillus gasseri 505 and Cudrania tricuspidata Leaf Extract Prevents Stress-Induced Testicular Dysfunction in Mice

JY Joung, W Lim, YJ Seo, J Ham, NS Oh… - Frontiers in …, 2022 - frontiersin.org
This study investigated the effects of a synbiotic combination (Syn) of Lactobacillus gasseri
505 (505) and Cudrania tricuspidata leaf extract (CT) on the hypothalamic-pituitary-gonadal …

Tortoise-shell glue ameliorates male infertility through the hypothalamic-pituitary-gonadal axis in obese rats

W Sheng, Y Li, L Liu, B Li, T Sun, C Zhu… - Animal Cells and …, 2024 - Taylor & Francis
Background Male infertility is a worldwide population health concern, but its etiology
remains poorly understood. Tortoise-shell glue (TSG) is widely utilized as a pharmaceutical …

Lycium barbarum Polysaccharides Improve Testicular Spermatogenic Function in Streptozotocin-Induced Diabetic Rats

X Lei, P Huo, Y Wang, Y Xie, Q Shi, H Tu… - Frontiers in …, 2020 - frontiersin.org
The objective of this study was to investigate the protective effects of Lycium barbarum
polysaccharides (LBP) on testicular spermatogenic function in streptozotocin (STZ)-induced …

Exploration of Lactiplantibacillus plantarum P101 ameliorated the alcohol-induced testicular dysfunction based on metabolome analysis

P Nie, S Wen, M Wang, H Xu - Food and Chemical Toxicology, 2024 - Elsevier
The decline in male sperm quality caused by multiple factors has become a widespread
concern. Alcohol excessive consumption is one of the factors that induce testicular …

The therapeutic role of lactobacillus and montelukast in combination with metformin in diabetes mellitus complications through modulation of gut microbiota and …

AM El-Baz, A Shata, HM Hassan… - International …, 2021 - Elsevier
Male reproductive dysfunction is one of the overlooked findings of diabetes mellitus (DM)
that deserves greater scientific attention. This study is designed to explore the therapeutic …

Garden Cress Seed Oil Abrogates Testicular Oxidative Injury and NF-kB-Mediated Inflammation in Diabetic Mice

R Abu-Khudir, GM Badr, HI Abd El-Moaty… - International Journal of …, 2023 - mdpi.com
Diabetes mellitus is a metabolic disorder associated with various complications
encompassing male reproductive dysfunction. The present study aimed to investigate the …