A potential association between immunosenescence and high COVID-19 related mortality among elderly patients with cardiovascular diseases

Y Wang, SC Pang, Y Yang - Immunity & Ageing, 2021 - Springer
Elderly patients with cardiovascular diseases account for a large proportion of Corona virus
Disease 2019 (COVID-19) related deaths. COVID-19, as a new coronavirus, mainly targets …

Aging, inflammaging and immunosenescence as risk factors of severe COVID-19

AM Tizazu, HM Mengist, G Demeke - Immunity & Ageing, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …

Immunosenescence and inflamm-ageing in COVID-19

MR Zinatizadeh, PK Zarandi, M Ghiasi… - Ageing Research …, 2023 - Elsevier
The destructive effects of coronavirus disease 2019 (COVID-19) on the elderly and people
with cardiovascular disease have been proven. New findings shed light on the role of aging …

Patho-physiology of aging and immune-senescence: possible correlates with comorbidity and mortality in middle-aged and old COVID-19 patients

S Farheen, S Agrawal, S Zubair, A Agrawal… - Frontiers in …, 2021 - frontiersin.org
During the last 2 years, the entire world has been severely devastated by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic (COVID-19) as it resulted in …

[HTML][HTML] An account of immune senescence in the clinical pathophysiology of COVID-19 infection in aging

S Jain, E Abrham, MN Khan, R Mathur - Aging and disease, 2021 - ncbi.nlm.nih.gov
Worldwide COVID-19 infection poses an enormous risk to public health and an alarming
global socioeconomic burden. The impact of the COVID-19 pandemic on individuals with …

Remodeling of the immune response with aging: immunosenescence and its potential impact on COVID-19 immune response

LL Cunha, SF Perazzio, J Azzi, P Cravedi… - Frontiers in …, 2020 - frontiersin.org
Elderly individuals are the most susceptible to an aggressive form of coronavirus disease
(COVID-19), caused by SARS-CoV-2. The remodeling of immune response that is observed …

Immune response to COVID-19 in older adults

M Jergović, CP Coplen, JL Uhrlaub… - The Journal of Heart and …, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the third highly
pathogenic coronavirus to emerge in the human population in last two decades. SARS-CoV …

I mmunosenescence and inflammaging: risk factors of severe COVID-19 in older people

AJ Pietrobon, FME Teixeira, MN Sato - Frontiers in immunology, 2020 - frontiersin.org
Old individuals are more susceptible to various infections due to immunological changes
that occur during the aging process. These changes named collectively as …

Immunopathology and immunosenescence, the immunological key words of severe COVID-19. Is there a role for stem cell transplantation?

ME Ligotti, F Pojero, G Accardi, A Aiello… - Frontiers in Cell and …, 2021 - frontiersin.org
The outcomes of Coronavirus disease-2019 (COVID-19) vary depending on the age, health
status and sex of an individual, ranging from asymptomatic to lethal. From an immunologic …

Age-related changes in plasma biomarkers and their association with mortality in COVID-19

EHA Michels, B Appelman… - European …, 2023 - Eur Respiratory Soc
Background Coronavirus disease 2019 (COVID-19)-induced mortality occurs predominantly
in older patients. Several immunomodulating therapies seem less beneficial in these …