The antibody immune response is essential for the survival of mammals. However, we still
lack a systematic understanding of the antibody repertoire. Here, we developed a proteomic …

The immunization of an animal with a whole proteome or the infection of an animal and the
screening of the resulting antibody repertoire on either the same or different proteome (s) or …

Nanobodies bind a target antigen with a kinetic profile similar to a conventional antibody, but
exist as a single heavy chain domain that can be readily multimerized to engage antigen via …

Variable domains of heavy chain-only antibodies (VHH), also known as nanobodies (Nbs),
are monomeric antigen-binding domains derived from the camelid heavy chain-only …

The unique class of heavy chain–only antibodies, present in Camelidae, can be shrunk to
just the variable region of the heavy chain to yield VHHs, also called nanobodies. About one …

Camelid single-domain antibody fragments ('nanobodies') provide the remarkable specificity
of antibodies within a single 15-kDa immunoglobulin VHH domain. This unique feature has …

Nanobodies are single-domain antibodies derived from the variable regions of Camelidae
atypical immunoglobulins. They show promise as high-affinity reagents for research …

Nanobodies are a class of antigen‐binding protein derived from camelids that achieve
comparable binding affinities and specificities to classical antibodies, despite comprising …

Polyclonal and monoclonal antibodies have been invaluable tools to study proteins over the
past decades. While indispensable for most biological studies including developmental …

Nanobodies, a unique subclass of antibodies first discovered in camelid animals, are
composed solely of a single heavy chain's variable region. Their significantly reduced …