[HTML][HTML] The protective effects of peroxisome proliferator-activated receptor gamma in cerebral ischemia-reperfusion injury

Y Ding, J Kang, S Liu, Y Xu, B Shao - Frontiers in Neurology, 2020 - frontiersin.org
Cerebral ischemia-reperfusion injury (CI/RI) is a complex pathological process that often
occurs secondary to trauma, surgery, and shock. Peroxisome proliferator activated receptor …

Peroxisome proliferator-activated receptor-gamma (PPAR-ɣ): molecular effects and its importance as a novel therapeutic target for cerebral ischemic injury

A Mannan, N Garg, TG Singh, HK Kang - Neurochemical Research, 2021 - Springer
Cerebral ischemic injury is a leading cause of death and long-term disability throughout the
world. Peroxisome proliferator-activated receptor gamma (PPAR-ɣ) is a ligand-activated …

[HTML][HTML] Peroxisome proliferator activated receptor-γ and traumatic brain injury

L Qi, A Jacob, P Wang, R Wu - International journal of clinical and …, 2010 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) represents a major health care problem and a significant
socioeconomic challenge worldwide. No specific therapy for TBI is available. The …

Roles of peroxisome proliferator-activated receptor gamma on brain and peripheral inflammation

S Villapol - Cellular and molecular neurobiology, 2018 - Springer
Peroxisome proliferator-activated receptor gamma (PPARγ) has been implicated in the
pathology of numerous diseases involving diabetes, stroke, cancer, or obesity. It is …

Neuroprotection against focal ischemic brain injury by the peroxisome proliferator‐activated receptor‐γ agonist rosiglitazone

Y Luo, W Yin, AP Signore, F Zhang… - Journal of …, 2006 - Wiley Online Library
Peroxisome proliferator‐activated receptor gamma (PPAR‐γ) is a nuclear membrane‐
associated transcription factor that governs the expression of various inflammatory genes …

Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair

W Cai, T Yang, H Liu, L Han, K Zhang, X Hu… - Progress in …, 2018 - Elsevier
Peroxisome proliferator-activated receptor γ (PPARγ) is a widely expressed ligand-
modulated transcription factor that governs the expression of genes involved in …

Neurovascular protection by peroxisome proliferator-activated receptor α in ischemic stroke

AC Boese, JP Lee, MH Hamblin - Experimental Neurology, 2020 - Elsevier
Ischemic stroke is a leading cause of death and disability worldwide. Currently, the only
pharmacological therapy for ischemic stroke is thrombolysis with tissue plasminogen …

Peroxisome proliferator-activated receptor γ promotes neuroprotection by modulating cyclic D1 expression after focal cerebral ischemia

L Pei, Y Zhang, Y Zhang, X Chu… - Canadian journal of …, 2010 - cdnsciencepub.com
Peroxisome proliferator-activated receptor γ (PPARγ) has been shown to protect against
stroke and improve neurological outcome after cerebral ischemia. This study investigated …

[HTML][HTML] PPARγ in ischemia-reperfusion injury: overview of the biology and therapy

R Huang, C Zhang, X Wang, H Hu - Frontiers in Pharmacology, 2021 - frontiersin.org
Ischemia-reperfusion injury (IRI) is a complex pathophysiological process that is often
characterized as a blood circulation disorder caused due to various factors (such as …

Altered PPARγ expression and activation after transient focal ischemia in rats

NA Victor, EW Wanderi, J Gamboa… - European Journal of …, 2006 - Wiley Online Library
Stroke is a devastating disease with limited treatment options. Recently, we found that the
peroxisome proliferator‐activated receptor‐γ (PPARγ) agonists troglitazone and …