[HTML][HTML] Angiotensin-(1-7) attenuates angiotensin II-induced ICAM-1, VCAM-1, and MCP-1 expression via the MAS receptor through suppression of P38 and NF-κB …

B Liang, X Wang, N Zhang, H Yang, R Bai… - Cellular Physiology and …, 2015 - karger.com
Background/Aims: Atherosclerosis is a chronic inflammatory disease. Intracellular adhesion
molecule-1 (ICAM-1), vascular cellular adhesion molecule-1 (VCAM-1), and monocyte …

Angiotensin-(1–7) regulates Angiotensin II-induced VCAM-1 expression on vascular endothelial cells

F Zhang, J Ren, K Chan, H Chen - Biochemical and biophysical research …, 2013 - Elsevier
Angiotensin II (Ang II) and Angiotensin-(1–7)(Ang-(1–7)) are key effector peptides in the
renin–angiotensin system. Increased circulatory Ang II level is associated with the …

Angiotensin-(1–7) abrogates angiotensin II-induced proliferation, migration and inflammation in VSMCs through inactivation of ROS-mediated PI3K/Akt and MAPK …

F Zhang, X Ren, M Zhao, B Zhou, Y Han - Scientific Reports, 2016 - nature.com
The proliferation, migration and inflammation of vascular smooth muscle cells (VSMCs)
contribute to the pathogenesis and progression of several cardiovascular diseases such as …

Angiotensin II stimulates endothelial vascular cell adhesion molecule-1 via nuclear factor-κB activation induced by intracellular oxidative stress

ME Pueyo, W Gonzalez, A Nicoletti… - … , and vascular biology, 2000 - Am Heart Assoc
The recruitment of monocytes via the endothelial expression of vascular cell adhesion
molecule-1 (VCAM-1) is a key step in the formation of the initial lesion in atherosclerosis …

The angiotensin-(1-7)/mas axis counteracts angiotensin II-dependent and-independent pro-inflammatory signaling in human vascular smooth muscle cells

LA Villalobos, Á San Hipólito-Luengo… - Frontiers in …, 2016 - frontiersin.org
Background and Aims: Targeting inflammation is nowadays considered as a challenging
pharmacological strategy to prevent or delay the development of vascular diseases …

Angiotensin II induces vascular cell adhesion molecule-1 expression in rat vasculature: a potential link between the renin-angiotensin system and atherosclerosis

PE Tummala, XL Chen, CL Sundell, JB Laursen… - Circulation, 1999 - Am Heart Assoc
Background—Cardiovascular ischemic events may occur more frequently in hypertensive
patients with activated renin-angiotensin systems. We tested the hypothesis that angiotensin …

Epigallocatechin-3-O-gallate inhibits the angiotensin II-induced adhesion molecule expression in human umbilical vein endothelial cell via inhibition of MAPK …

YJ Chae, CH Kim, TS Ha, J Hescheler… - Cellular Physiology and …, 2007 - karger.com
Abstract Epigallocatechin-3-O-gallate (EGCG) is the main catechin, which is derived from
Camellia sinensis plant. Vascular cell adhesion molecules (VCAMs) and intercellular …

Angiotensin II induces matrix metalloproteinase-9 expression via a nuclear factor-kappaB-dependent pathway in vascular smooth muscle cells

R Guo, L Yang, H Wang, B Liu, L Wang - Regulatory peptides, 2008 - Elsevier
Angiotensin II (AngII) is widely recognized as a critical regulator of the development of
atherosclerosis. Matrix metalloproteinases (MMPs) are thought to participate in plaque …

Angiotensin 1-7 protects against angiotensin II-induced endoplasmic reticulum stress and endothelial dysfunction via mas receptor

D Murugan, YS Lau, WC Lau, MR Mustafa, Y Huang - PloS one, 2015 - journals.plos.org
Angiotensin 1–7 (Ang 1–7) counter-regulates the cardiovascular actions of angiotensin II
(Ang II). The present study investigated the protective effect of Ang 1–7 against Ang II …

Angiotensin (1–7) ameliorates angiotensin II-induced inflammation by inhibiting LOX-1 expression

L Wang, X Hu, W Zhang, F Tian - Inflammation Research, 2013 - Springer
Objective and design Endothelial dysfunction plays an important role in all stages of
atherosclerosis and is characterized by an increased proinflammatory response. This study …