Adverse reactions with levamisole vary according to its indications and misuse: A systematic pharmacovigilance study

JT Campillo, C Eiden, M Boussinesq… - British Journal of …, 2022 - Wiley Online Library
Levamisole was initially prescribed for the treatment of intestinal worms. Because of
immunomodulatory properties, levamisole has been used in inflammatory pathologies and …

Levamisole—a toxic adulterant in illicit drug preparations: a review

KM Midthun, LS Nelson, BK Logan - Therapeutic Drug Monitoring, 2021 - journals.lww.com
Discovered in the 1960s, the common anthelminthic levamisole has seen widespread use in
veterinary applications. Its use rapidly expanded thereafter to include human medical …

Levamisole in cocaine: unexpected news from an old acquaintance

A Larocque, RS Hoffman - Clinical Toxicology, 2012 - Taylor & Francis
Levamisole is a pharmaceutical with anthelminthic and immunomodulatory properties that
was previously used in both animals and humans to treat inflammatory conditions and …

Levamisole in dermatology: a review

N Scheinfeld, JD Rosenberg, JM Weinberg - American journal of clinical …, 2004 - Springer
Levamisole, an anthelmintic agent with a wide range of immunomodulatory actions, has
been used successfully as monotherapy and an adjunct to treatment in a variety of diseases …

Prevalence of levamisole and aminorex in patients tested positive for cocaine in a French University Hospital

C Eiden, H Peyrière, C Diot, O Mathieu - Clinical toxicology, 2015 - Taylor & Francis
Context. The prevalence of levamisole in urine samples of subjects positive for cocaine in
the US was estimated at 78%(95% confidence interval or CI: 73%–83%). However …

[引用][C] Recent clinical trials with levamisole

MR Kurman - Annals of the New York Academy of Sciences, 1993 - Wiley Online Library
Levamisole, an anthelmintic discovered in the 1960s, was serendipitously found to have
immunomodulating effects in 1971, when it was shown to enhance the protective effect of a …

Detection of levamisole exposure in cocaine users by liquid chromatography-tandem mass spectrometry

KL Lynch, SS Dominy, J Graf… - Journal of analytical …, 2011 - academic.oup.com
Levamisole, a veterinary antihelminthic, was recently recognized as an adulterant in cocaine
and is known to cause severe adverse reactions in some cocaine users. Because of the …

[HTML][HTML] Levamisole-induced vasculitis

L Sayadi, D Laub - Eplasty, 2018 - ncbi.nlm.nih.gov
DISCUSSION Levamisole is a synthetic imidazathiazole antihelminthic agent once used
medically for its immunomodulatory effects; its use in the medical setting was curtailed in …

Adverse effects of levamisole in cocaine users: a review and risk assessment

TM Brunt, J van den Berg, E Pennings, B Venhuis - Archives of Toxicology, 2017 - Springer
The immunomodulatory adjuvant and antihelminth levamisole is increasingly used as an
adulterant in cocaine worldwide. An accumulating body of clinical and toxicological literature …

Complications associated with use of levamisole-contaminated cocaine: an emerging public health challenge

KC Lee, B Ladizinski, DG Federman - Mayo Clinic Proceedings, 2012 - Elsevier
Levamisole is an immunomodulatory agent that was used to treat various cancers before
being withdrawn from the United States market in 2000 because of adverse effects …