[HTML][HTML] Off-the-shelf CAR natural killer cells secreting IL-15 target spike in treating COVID-19
Engineered natural killer (NK) cells represent a promising option for immune therapy option
due to their immediate availability in allogeneic settings. Severe acute diseases, such as …
due to their immediate availability in allogeneic settings. Severe acute diseases, such as …
[HTML][HTML] CAR-NK Cells Effectively Target SARS-CoV-2-Spike-Expressing Cell Lines In Vitro
MT Ma, S Badeti, CH Chen, J Kim… - Frontiers in …, 2021 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is highly contagious and
presents a significant public health issue. Current therapies used to treat coronavirus …
presents a significant public health issue. Current therapies used to treat coronavirus …
[HTML][HTML] Glycoprotein targeted CAR-NK cells for the treatment of SARS-CoV-2 infection
I Christodoulou, R Rahnama, JW Ravich… - Frontiers in …, 2021 - frontiersin.org
H84T-Banana Lectin (BanLec) CAR-NK cells bind high mannose glycosites that decorate
the SARS-CoV-2 envelope, thereby decreasing cellular infection in a model of SARS-CoV-2 …
the SARS-CoV-2 envelope, thereby decreasing cellular infection in a model of SARS-CoV-2 …
[HTML][HTML] SARS-CoV-2 spike 1 protein controls natural killer cell activation via the HLA-E/NKG2A pathway
Natural killer cells are important in the control of viral infections. However, the role of NK
cells during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has …
cells during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has …
[HTML][HTML] SARS-CoV-2 Nsp13 encodes for an HLA-E-stabilizing peptide that abrogates inhibition of NKG2A-expressing NK cells
Natural killer (NK) cells are innate immune cells that contribute to host defense against virus
infections. NK cells respond to severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
infections. NK cells respond to severe acute respiratory syndrome coronavirus 2 (SARS-CoV …
[HTML][HTML] Flattening the COVID-19 curve with natural killer cell based immunotherapies
M Market, L Angka, AB Martel, D Bastin… - Frontiers in …, 2020 - frontiersin.org
Natural Killer (NK) cells are innate immune responders critical for viral clearance and
immunomodulation. Despite their vital role in viral infection, the contribution of NK cells in …
immunomodulation. Despite their vital role in viral infection, the contribution of NK cells in …
Siglec-9 restrains antibody-dependent natural killer cell cytotoxicity against SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection alters the
immunological profiles of natural killer (NK) cells. However, whether NK antiviral functions …
immunological profiles of natural killer (NK) cells. However, whether NK antiviral functions …
[HTML][HTML] Can natural killer cells be a principal player in anti-SARS-CoV-2 immunity?
The spread of the coronavirus disease 2019 (COVID-19) pandemic has led to disastrous
consequences, impacting social, economic, and medical systems, spanning both developed …
consequences, impacting social, economic, and medical systems, spanning both developed …
Natural killer cells in SARS-CoV-2-vaccinated subjects with increased effector cytotoxic cd56dim cells and memory-like CD57+ NKG2C+ CD56dim cells
Background: The infection and negative effects of the SARS-CoV-2 (severe acute respiratory
syndrome coronavirus) virus are mitigated by vaccines. It is unknown whether vaccination …
syndrome coronavirus) virus are mitigated by vaccines. It is unknown whether vaccination …