Dual-specificity tyrosine phosphorylation-regulated kinase 1 A (DYRK1A) is a conserved
protein kinase that plays essential roles in various biological processes. It is located in the …

Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a member of an
evolutionarily conserved family of protein kinases that belongs to the CMGC group of …

Alzheimer, the fourth leading cause of death embodies a key responsible event including
formation of β-amyloid protein clustering to amyloid plaque on blood vessels. The origin of …

Abstract The Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) is
an enzyme that has been implicated as an important drug target in various therapeutic …

Protein kinases are one of the most studied drug targets in current pharmacological
research, as evidenced by the vast number of kinase-targeting agents enrolled in active …

With 24.3 million people affected in 2005 and an estimated rise to 42.3 million in 2020,
dementia is currently a leading unmet medical need and costly burden on public health …

Introduction: Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A) is a
eukaryotic serine-threonine protein kinase belonging to the CMGC group. DYRK1A …

The serine/threonine kinase DYRK1A has been implicated in regulation of a variety of
cellular processes associated with cancer progression, including cell cycle control, DNA …

Various types of cancers (including gliomas, melanomas, and esophageal, pancreas and
non-small-cell lung cancers) display intrinsic resistance to pro-apoptotic stimuli, such as …

In total, 47,500,000 people worldwide are affected by dementia and this number is estimated
to double by 2030 and triple within 2050 resulting in a huge burden on public health …