Mutational landscape and interaction of SARS-CoV-2 with host cellular components

M Srivastava, D Hall, OB Omoru, HM Gill, S Smith… - Microorganisms, 2021 - mdpi.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its
rapid evolution has led to a global health crisis. Increasing mutations across the SARS-CoV …

Cellular host factors for SARS-CoV-2 infection

J Baggen, E Vanstreels, S Jansen, D Daelemans - Nature Microbiology, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has claimed millions of lives
and caused a global economic crisis. No effective antiviral drugs are currently available to …

SARS-CoV-2: pathogenesis, therapeutics, variants, and vaccines

X Li, Z Mi, Z Liu, P Rong - Frontiers in Microbiology, 2024 - frontiersin.org
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), emerged in December 2019 with staggering economic fallout …

SARS-CoV-2 variants: Impact on biological and clinical outcome

S Mahilkar, S Agrawal, S Chaudhary, S Parikh… - Frontiers in …, 2022 - frontiersin.org
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) that was first identified
in December 2019, in Wuhan, China was found to be the etiological agent for a novel …

Intra-host evolution during SARS-CoV-2 prolonged infection

CM Voloch, R da Silva Francisco Jr… - Virus …, 2021 - academic.oup.com
Long-term infection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
represents a challenge to virus dispersion and the control of coronavirus disease 2019 …

SARS-CoV-2: an update on the biological interplay with the human host

G Lippi, F Sanchis-Gomar, C Mattiuzzi, BM Henry - COVID, 2023 - mdpi.com
Coronavirus Disease 2019 (COVID-19) is an infectious respiratory illness caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The disease, first identified in the …

Evolving infection paradox of SARS-CoV-2: fitness costs virulence?

ASMRU Alam, OK Islam, MS Hasan, MR Islam… - MedRxiv, 2021 - medrxiv.org
Background SARS-CoV-2 is continuously spreading worldwide at an unprecedented scale
and evolved into seven clades according to GISAID where four (G, GH, GR and GV) are …

Major insights in dynamics of host response to SARS-CoV-2: impacts and challenges

A Hakim, MM Hasan, M Hasan, SM Lokman… - Frontiers in …, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19), a pandemic declared by the World Health
Organization on March 11, 2020, is caused by the infection of highly transmissible species of …

SARS-CoV-2 biology and host interactions

S Steiner, A Kratzel, GT Barut, RM Lang… - Nature Reviews …, 2024 - nature.com
The zoonotic emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing coronavirus disease 2019 (COVID-19) pandemic have profoundly affected …

SARS-CoV-2 variants evolve convergent strategies to remodel the host response

M Bouhaddou, AK Reuschl, BJ Polacco, LG Thorne… - Cell, 2023 - cell.com
SARS-CoV-2 variants of concern (VOCs) emerged during the COVID-19 pandemic. Here,
we used unbiased systems approaches to study the host-selective forces driving VOC …