Glioblastoma remains a clinical challenge in spite of years of extensive research. Novel
approaches are needed in order to integrate the existing knowledge. This is the potential …

Glioblastoma extensively infiltrates the brain; despite surgery and aggressive therapies, the
prognosis is poor. A multidisciplinary approach combining mathematical, clinical and …

Glioblastoma multiforme (GBM) is the most malignant form of primary brain tumors known as
gliomas. They proliferate and invade extensively and yield short life expectancies despite …

Background. We present a mathematical model for grade II glioma progression and
response to radiotherapy (RT) able to predict the long-time response to treatment. Materials …

Simple Summary In this review, the thorny issue of glioblastoma models is addressed, with a
focus on 3D in vitro models. In the first part of the manuscript, glioblastoma features and …

Critical Parameters Determining Standard Radiotherapy Treatment Outcome for Glioblastoma
Multiforme: A Computer Simulation - PMC Back to Top Skip to main content NIH NLM Logo …

Gliomas are the most common primary brain tumors in adults and carry a dismal prognosis
for patients. Current standard-of-care for gliomas is comprised of maximal safe surgical …

Background Radiomics-based prediction of glioblastoma spatial progression and
recurrence may improve personalized strategies. However, most prototypes are based on …

Simple Summary Glioblastoma multiforme is an aggressive brain tumor with a poor survival
rate despite modern therapeutic options. In this context, advanced preclinical models and …

Purpose Precision medicine has been most successful in targeting single mutations, but
personalized medicine using broader genomic tumor profiles for individual patients is less …