Type III interferons (lambda IFNs) are a quite new, small family of three closely related
cytokines with interferon-like activity. Attention to IFN-λ is mainly focused on direct antiviral …

Type III interferons (IFNs)(interleukin-28/29 or lambda interferon [IFN-λ]) are cytokines with
IFN-like activities. Here we show that several classes of viruses induce expression of IFN-λ1 …

Interferons (IFNs) are generally considered antiviral cytokines, yet the newly discovered IFN-
λ4 is linked with the failure to clear hepatitis C virus (HCV) infection either spontaneously or …

The first line of defense against viral infections is mediated by interferons (IFN) s, which are
produced rapidly by the infected host. Type I IFNs (IFN-α/β) are known to combat viruses …

Interferons (IFNs) can serve as the first line of immune defense against viral infection. The
identification of IFN-λs 1, 2, 3 & 4 (termed as type III IFNs) has revealed that the antiviral …

Interferons (IFN) exert antiviral, immunomodulatory and cytostatic activities. IFN-α/β (type I
IFN) and IFN-λ (type III IFN) bind distinct receptors, but regulate similar sets of genes and …

Type III interferons, also known as interferon lambdas (IFNλs), are the most recent addition
to the IFN family following their discovery in 2003. Initially, IFNλ was demonstrated to induce …

The discovery and initial description of the interferon-λ (IFN-λ) family in early 2003 opened
an exciting new chapter in the field of IFN research. There are 3 IFN-λ genes that encode 3 …

Interferon (IFN)-λ forms the type III IFN family. Although they signal through distinct receptors,
type I (IFN-α/β) and type III IFNs elicit remarkably similar responses in cells. However, in …

Type III interferons (IFN-lambda) are the most recently discovered members of IFN family.
Synergism between different IFN types is well established, but for type I and type III IFNs no …