Background Mood disorders (including major depressive disorder and bipolar disorder)
affect 10% to 20% of the population. They range from brief, mild episodes to severe …

Background Major depressive disorder (MDD) is a disabling mood disorder, and despite a
known heritable component, a large meta-analysis of genome-wide association studies …

Prior genome-wide association studies (GWAS) of major depressive disorder (MDD) have
met with limited success. We sought to increase statistical power to detect disease loci by …

Prior genome-wide association studies (GWAS) of major depressive disorder (MDD) have
met with limited success. We sought to increase statistical power to detect disease loci by …

Major depressive disorder (MDD) is a common complex disorder with a partly genetic
etiology. We conducted a genome-wide association study of the MDD2000+ sample (2431 …

The major mood disorders, which include bipolar disorder and major depressive disorder
(MDD), are considered heritable traits, although previous genetic association studies have …

Substantial indirect evidence suggests overlap between bipolar disorder (BIP) and major
depressive disorder (MDD). BIP and MDD have in common major depressive episodes with …

Genome-wide association studies (GWAS) of psychiatric phenotypes have tended to focus
on categorical diagnoses, but to understand the biology of mental illness it may be more …

Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …

Background The genetics of depression has been explored in genome-wide association
studies that focused on either major depressive disorder or depressive symptoms with …