Abstract Epigenome-Wide Association Study (EWAS) has become a standard strategy to discover DNA methylation variation of different phenotypes. Since 2018, we have developed …
T Battram, P Yousefi, G Crawford, C Prince… - Wellcome open …, 2022 - ncbi.nlm.nih.gov
Epigenome-wide association studies (EWAS) seek to quantify associations between traits/exposures and DNA methylation measured at thousands or millions of CpG sites …
Background Epigenome-wide association scans (EWAS) are an increasingly powerful and widely-used approach to assess the role of epigenetic variation in human complex traits …
The aetiology and pathophysiology of complex diseases are driven by the interaction between genetic and environmental factors. The variability in risk and outcomes in these …
Abstract Epigenome-Wide Association Study (EWAS) has become an effective strategy to explore epigenetic basis of complex traits. Over the past decade, a large amount of …
Epigenome-wide association studies (EWAS) provide an alternative approach for studying human disease through consideration of non-genetic variants such as altered DNA …
VK Rakyan, TA Down, DJ Balding, S Beck - Nature Reviews Genetics, 2011 - nature.com
Despite the success of genome-wide association studies (GWASs) in identifying loci associated with common diseases, a substantial proportion of the causality remains …
MJ Li, LY Wang, Z Xia, PC Sham… - Nucleic acids research, 2013 - academic.oup.com
Interpreting the genetic variants located in the regulatory regions, such as enhancers and promoters, is an indispensable step to understand molecular mechanism of complex traits …
We created a deeply extracted and annotated database of genome-wide association studies (GWAS) results. GRASP v1. 0 contains> 6.2 million SNP-phenotype association from among …