Mechanism of ferroptosis in breast cancer and research progress of natural compounds regulating ferroptosis

A Ge, Q He, D Zhao, Y Li, J Chen… - Journal of Cellular …, 2024 - Wiley Online Library
Breast cancer is the most prevalent cancer worldwide and its incidence increases with age,
posing a significant threat to women's health globally. Due to the clinical heterogeneity of …

Targeting ferroptosis, the achilles' heel of breast cancer: A review

Y Liu, Y Hu, Y Jiang, J Bu, X Gu - Frontiers in Pharmacology, 2022 - frontiersin.org
Ferroptosis is referred as a novel type of cell death discovered in recent years with the
feature of the accumulation of iron-dependent lipid reactive oxygen species. Breast cancer is …

Emerging role of ferroptosis in breast cancer: New dawn for overcoming tumor progression

S Sui, S Xu, D Pang - Pharmacology & therapeutics, 2022 - Elsevier
Breast cancer has become a serious threat to women's health. Cancer progression is mainly
derived from resistance to apoptosis induced by procedures or therapies. Therefore, new …

Phytochemicals targeting ferroptosis: therapeutic opportunities and prospects for treating breast cancer

X Zhao, X Wang, Y Pang - Pharmaceuticals, 2022 - mdpi.com
Ferroptosis, a recently discovered iron-dependent regulated cell death, has been implicated
in the therapeutic responses of various cancers including breast cancer, making it a …

Compounds targeting ferroptosis in breast cancer: progress and their therapeutic potential

C Xu, Y Chen, Q Yu, J Song, Y Jin, X Gao - Frontiers in Pharmacology, 2023 - frontiersin.org
In recent years, there has been a significant increase in the incidence of Breast cancer (BC),
making it the most common cancer among women and a major threat to women's health …

Inducing ferroptosis has the potential to overcome therapy resistance in breast cancer

X Qi, Z Wan, B Jiang, Y Ouyang, W Feng… - Frontiers in …, 2022 - frontiersin.org
Breast cancer is the most common type of malignancy among women. Due to the iron-
dependent character of breast cancer cells, they are more sensitive to ferroptosis compared …

The evolving role of ferroptosis in breast cancer: translational implications present and future

HY Lin, HW Ho, YH Chang, CJ Wei, PY Chu - Cancers, 2021 - mdpi.com
Simple Summary Despite decades of extensive study into targeting cell death in breast
cancer, including apoptosis, the clinical treatment remains challenging due to its high …

Heme oxygenase modulation drives ferroptosis in TNBC cells

V Consoli, V Sorrenti, V Pittalà, K Greish… - International journal of …, 2022 - mdpi.com
The term ferroptosis refers to a peculiar type of programmed cell death (PCD) mainly
characterized by extensive iron-dependent lipid peroxidation. Recently, ferroptosis has been …

[HTML][HTML] Conceptualizing the complexity of ferroptosis to treat triple-negative breast cancer: theory-to-practice

H Zhang, F Yang, Y Xiao, YZ Jiang… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Ferroptosis, a type of regulated cell death named one decade ago, is a unique type driven
by lipid peroxidation in an iron-dependent manner. Ferroptosis differs radically from …

Research Progress on Ferroptosis and Nanotechnology-Based Treatment in Triple-Negative Breast Cancer

J Zhang, S Zhang, M Liu, Z Yang… - Breast Cancer: Targets …, 2024 - Taylor & Francis
In recent years, more and more researches on cell death mode in breast cancer, including
apoptosis, ferroptosis, etc. Ferroptosisis a regulated form of cell death characterized by iron …