Background While individual cardiac myocytes only have a limited ability to shorten, the
heart efficiently pumps a large volume-fraction thanks to a cell organization in a complex 3D …

Cardiovascular diseases (CVDs) affect the myocardium and vasculature, inducing
remodelling of the heart from cellular to whole organ level. To assess their impact at micro …

Cardiovascular research is in an ongoing quest for a superior imaging method to integrate
gross-anatomical information with microanatomy, combined with quantifiable parameters of …

This paper investigates the 3D microscopic structure of ex-vivo human cardiac muscle.
Usual 3D imaging techniques such as DMRI or CT do not achieve the required resolution to …

Purpose: We present a phase-contrast x-ray tomography study of wild type C57BL/6 mouse
hearts as a nondestructive approach to the microanatomy on the scale of the entire excised …

Complex helical organization of cardiac fibers is one of the key factors for efficient beat-to-
beat contraction and electrical impulse propagation. Complete understanding of this (inter …

Background Current clinical imaging modalities such as CT and MRI provide resolution
adequate to diagnose cardiovascular diseases but cannot depict detailed structural features …

High-spatial-resolution histology of coronary artery autopsy samples play an important role
for understanding heart disease such as myocardial infarction. Unfortunately, classical …

Abstract At SPring-8, synchrotron radiation-based X-ray phase-contrast tomography (PCXI)
has been developed to measure the inner structures of biological soft tissue without …

Cardiovascular malformations and diseases are common but complex and often not yet fully
understood. To better understand the effects of structural and microstructural changes of the …