The conundrum of lung disease and drug hypersensitivity‐like reactions in systemic juvenile idiopathic arthritis
BA Binstadt, PA Nigrovic - Arthritis & rheumatology, 2022 - Wiley Online Library
An unusual form of lung disease has begun to affect some children with systemic juvenile
idiopathic arthritis (JIA), coincident with increasing utilization of interleukin‐1 (IL‐1) and IL‐6 …
idiopathic arthritis (JIA), coincident with increasing utilization of interleukin‐1 (IL‐1) and IL‐6 …
Diagnosis and management of the systemic juvenile idiopathic arthritis patient with emerging lung disease
C Towe, AA Grom, GS Schulert - Pediatric Drugs, 2023 - Springer
Chronic lung disease in children with systemic juvenile idiopathic arthritis (SJIA-LD) is an
emerging and potentially life-threatening disease complication. Despite recent descriptions …
emerging and potentially life-threatening disease complication. Despite recent descriptions …
HLA–DRB1* 15 and Eosinophilia Are Common Among Patients With Systemic Juvenile Idiopathic Arthritis
AM Lerman, SA Mahmud, Z Alfath… - Arthritis care & …, 2023 - Wiley Online Library
Objective Concern exists that medications used to treat patients with systemic juvenile
idiopathic arthritis (JIA), particularly interleukin (IL)‐1 and IL‐6 blocking agents, might be …
idiopathic arthritis (JIA), particularly interleukin (IL)‐1 and IL‐6 blocking agents, might be …
Recombinant Interleukin‐1 Receptor antagonist is an effective first‐line treatment strategy in new‐onset systemic Juvenile Idiopathic Arthritis, irrespective of HLA …
RGA Erkens, JJA Calis, A Verwoerd… - Arthritis & …, 2023 - Wiley Online Library
Objective HLA‐DRB1* 15: 01 has been recently associated with interstitial lung disease
(LD), eosinophilia, and drug reactions in systemic juvenile idiopathic arthritis (sJIA) …
(LD), eosinophilia, and drug reactions in systemic juvenile idiopathic arthritis (sJIA) …
Systemic juvenile idiopathic arthritis: new insights into pathogenesis and cytokine directed therapies
M Pardeo, C Bracaglia, F De Benedetti - Best practice & research Clinical …, 2017 - Elsevier
Systemic juvenile idiopathic arthritis (sJIA) is considered as a polygenic autoinflammatory
disease. The prominent systemic clinical features, the marked elevation of inflammatory …
disease. The prominent systemic clinical features, the marked elevation of inflammatory …
[HTML][HTML] Disease Course, Treatments, and Outcomes of Children With Systemic Juvenile Idiopathic Arthritis–Associated Lung Disease
Y Huang, L Sompii-Montgomery, J Patti… - Arthritis care & …, 2024 - ncbi.nlm.nih.gov
Objective. Systemic juvenile idiopathic arthritis–associated lung disease (SJIA-LD) is a life-
threatening disease complication. Key questions remain regarding clinical course and …
threatening disease complication. Key questions remain regarding clinical course and …
Systemic juvenile idiopathic arthritis–associated lung disease: characterization and risk factors
GS Schulert, S Yasin, B Carey, C Chalk… - Arthritis & …, 2019 - Wiley Online Library
Objective Systemic juvenile idiopathic arthritis (JIA) is associated with a recently recognized,
albeit poorly defined and characterized, lung disease (LD). The objective of this study was to …
albeit poorly defined and characterized, lung disease (LD). The objective of this study was to …
Incidence and risk factors for eosinophilia and lung disease in biologic‐exposed children with systemic juvenile idiopathic arthritis
H Wobma, SR Arvila, ML Taylor, KP Lam… - Arthritis care & …, 2023 - Wiley Online Library
Objective Although interleukin‐1 (IL‐1)/IL‐6 inhibitors are effective therapies for systemic
juvenile idiopathic arthritis (JIA), some patients develop eosinophilia and lung disease …
juvenile idiopathic arthritis (JIA), some patients develop eosinophilia and lung disease …
Pathogenesis and treatment of refractory disease courses in systemic juvenile idiopathic arthritis: refractory arthritis, recurrent macrophage activation syndrome and …
R Erkens, Y Esteban, C Towe… - Rheumatic Disease …, 2021 - rheumatic.theclinics.com
Systemic juvenile idiopathic arthritis (sJIA) is generally seen as the most severe category of
JIA. These categories are distinct in their pathobiology, disease course and specific …
JIA. These categories are distinct in their pathobiology, disease course and specific …
The pattern of response to anti–interleukin‐1 treatment distinguishes two subsets of patients with systemic‐onset juvenile idiopathic arthritis
M Gattorno, A Piccini, D Lasigliè, S Tassi… - Arthritis & …, 2008 - Wiley Online Library
Objective To assess the clinical response to interleukin‐1 (IL‐1) blockade and in vitro IL‐1β
and IL‐18 secretion in patients with systemic‐onset juvenile idiopathic arthritis (JIA) …
and IL‐18 secretion in patients with systemic‐onset juvenile idiopathic arthritis (JIA) …