Defining dry eye from a clinical perspective

K Tsubota, SC Pflugfelder, Z Liu, C Baudouin… - International journal of …, 2020 - mdpi.com
Over the past decades, the number of patients with dry eye disease (DED) has increased
dramatically. The incidence of DED is higher in Asia than in Europe and North America …

[HTML][HTML] Definition and diagnostic criteria of dry eye disease: historical overview and future directions

J Shimazaki - Investigative ophthalmology & visual science, 2018 - tvst.arvojournals.org
The definition and diagnostic criteria of dry eye disease (DED) proposed by the Japan Dry
Eye Society and other countries are reviewed. The first definition and criteria of DED in …

The growing need for validated biomarkers and endpoints for dry eye clinical research

NS Roy, Y Wei, E Kuklinski… - … ophthalmology & visual …, 2017 - iovs.arvojournals.org
Purpose: Biomarkers with minimally invasive and reproducible objective metrics provide the
key to future paradigm shifts in understanding of the underlying causes of dry eye disease …

An objective approach to dry eye disease severity

BD Sullivan, D Whitmer, KK Nichols… - … & visual science, 2010 - iovs.arvojournals.org
Purpose.: A prospective, multisite clinical study (10 sites in the European Union and the
United States) evaluated the clinical utility of commonly used tests and tear osmolarity for …

Diagnostic procedures and management of dry eye

S Kaštelan, M Tomić… - BioMed research …, 2013 - Wiley Online Library
Dry eye disease or dysfunctional tear syndrome is among the most frequent diagnoses in
ophthalmology. It is a multifactorial disease of the ocular surface and tear film which results …

[HTML][HTML] Dry eye disease: A review of diagnostic approaches and treatments

H Lin, SC Yiu - Saudi Journal of Ophthalmology, 2014 - Elsevier
Dry eye (DE) is a common ocular disease that results in eye discomfort, visual disturbance
and substantially affects the quality of life. It has a multifactorial etiology involving tear film …

Advances in understanding and managing dry eye disease

MA Lemp - American journal of ophthalmology, 2008 - Elsevier
PURPOSE: To present evidence from the literature and scientific meetings to support
fundamental changes in concepts regarding the prevalence, pathogenesis, definition …

Associations between signs and symptoms of dry eye disease: a systematic review

JD Bartlett, MS Keith, L Sudharshan… - Clinical …, 2015 - Taylor & Francis
Purpose The accurate diagnosis and classification of dry eye disease (DED) is challenging
owing to wide variations in symptoms and lack of a single reliable clinical assessment. In …

Diagnosing the severity of dry eye: a clear and practical algorithm

C Baudouin, P Aragona, G Van Setten… - British Journal of …, 2014 - bjo.bmj.com
Dry eye disease (DED) is a distressing ocular condition. Due to its multifactorial nature,
clinical and biological signs of DED can be inconsistent and sometimes discordant with …

[PDF][PDF] Dry eye disease: pathophysiology, classification, and diagnosis

HD Perry - Am J Manag Care, 2008 - ajmc.s3.amazonaws.com
Dry eye disease (DED) is a multifactorial disorder of the tear film and ocular surface that
results in eye discomfort, visual disturbance, and often ocular surface damage. Although …