The new WHO classification of adrenal cortical proliferations reflects translational advances
in the fields of endocrine pathology, oncology and molecular biology. By adopting a …

Approximately one-tenth of the general population exhibit adrenal cortical nodules, and the
incidence has increased. Afflicted patients display a multifaceted symptomatology …

Context: Approximately half of patients with primary aldosteronism (PA) have clinically
evident disease according to clinical (hypertension) and/or laboratory (aldosterone and …

The fourth edition of the World Health Organization (WHO) classification of endocrine
tumours contains substantial new findings for the adrenal tumours. The tumours are …

The diagnosis of low-grade adrenal cortical carcinoma (ACC) confined to the adrenal gland
can be challenging. Although there are diagnostic and prognostic molecular tests for ACC …

BACKGROUND: A reclassification of the International Union Against Cancer (UICC) staging
system for adrenocortical carcinoma (ACC) patients has recently been proposed by the …

Neuroendocrine neoplasia is described in almost every tissue, either in the pure endocrine
organs, the nerve structures or in the so-called diffuse neuroendocrine system. The current …

Objective Develop a consensus for the nomenclature and definition of adrenal
histopathologic features in unilateral primary aldosteronism (PA). Context Unilateral PA is …

Discerning malignancy in adrenal tumors largely influences disease management and is,
therefore, of utmost importance to both patient and physician. Clinical presentation (eg …

Adrenocortical carcinomas are rare tumours that can be diagnostically challenging.
Numerous multiparametric scoring systems and diagnostic algorithms have been proposed …