MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence

JH Cho, M Dimri, GP Dimri - Journal of Biological Chemistry, 2015 - ASBMB
MicroRNAs (miRNAs) have emerged as important regulators of tumorigenesis. Several
miRNAs, which can function either as oncomiRs or tumor suppressive miRs are deregulated …

Mir-17-5p Regulates Breast Cancer Cell Proliferation by Inhibiting Translation of AIB1 mRNA

A Hossain, MT Kuo, GF Saunders - Molecular and cellular biology, 2006 - Taylor & Francis
MicroRNAs are an extensive family of∼ 22-nucleotide-long noncoding RNAs expressed in a
wide range of eukaryotes, including humans, and they are important in development and …

MiR-24 Tumor Suppressor Activity Is Regulated Independent of p53 and through a Target Site Polymorphism

PJ Mishra, B Song, PJ Mishra, Y Wang, R Humeniuk… - PloS one, 2009 - journals.plos.org
MicroRNAs (miRNAs) are predicted to regulate approximately 30% of all human genes;
however, only a few miRNAs have been assigned their targets and specific functions. Here …

[HTML][HTML] MicroRNA-31 functions as a tumor suppressor by regulating cell cycle and epithelial-mesenchymal transition regulatory proteins in liver cancer

HS Kim, KS Lee, HJ Bae, JW Eun, Q Shen, SJ Park… - Oncotarget, 2015 - ncbi.nlm.nih.gov
Abstract MicroRNA-31 (miR-31) is among the most frequently altered microRNAs in human
cancers and altered expression of miR-31 has been detected in a large variety of tumor …

The role of miR‐21 in cancer

SR Pfeffer, CH Yang, LM Pfeffer - Drug development research, 2015 - Wiley Online Library
ABSTRACT Preclinical Research MicroRNAs (miRNAs) are small endogenous noncoding
RNAs that suppress gene expression at the post‐transcriptional level. In the past decade …

[HTML][HTML] miR-107 promotes tumor progression by targeting the let-7 microRNA in mice and humans

PS Chen, JL Su, ST Cha, WY Tarn… - The Journal of …, 2011 - Am Soc Clin Investig
MicroRNAs (miRNAs) influence many biological processes, including cancer. They do so by
posttranscriptionally repressing target mRNAs to which they have sequence …

Overexpression of microRNA-96-5p inhibits autophagy and apoptosis and enhances the proliferation, migration and invasiveness of human breast cancer cells

Y Shi, Y Zhao, N Shao, R Ye, Y Lin… - Oncology …, 2017 - spandidos-publications.com
MicroRNAs (miRNA/miR) are short non-coding RNAs that function in the endogenous
regulation of genes. miRNAs serve important roles in cellular events such as apoptosis, cell …

MiR-34, SIRT1, and p53: the feedback loop

M Yamakuchi, CJ Lowenstein - Cell cycle, 2009 - Taylor & Francis
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. Several
studies have linked dysregulation of miRNA with tumorigenesis. The TP53 is one of the most …

The guardian's little helper: microRNAs in the p53 tumor suppressor network

X He, L He, GJ Hannon - Cancer research, 2007 - AACR
Several microRNAs (miRNAs) have been implicated in tumor development based on both
changes in their expression patterns and gene structural alterations in human tumors …

miR-22 represses cancer progression by inducing cellular senescence

D Xu, F Takeshita, Y Hino, S Fukunaga, Y Kudo… - Journal of Cell …, 2011 - rupress.org
Cellular senescence acts as a barrier to cancer progression, and microRNAs (miRNAs) are
thought to be potential senescence regulators. However, whether senescence-associated …