Microfluidic devices for detection of RNA viruses

A Basiri, A Heidari, MF Nadi… - Reviews in medical …, 2021 - Wiley Online Library
There is a long way to go before the coronavirus disease 2019 (Covid‐19) outbreak comes
under control. qRT‐PCR is currently used for the detection of severe acute respiratory …

Modular micro-PCR system for the onsite rapid diagnosis of COVID-19

PQM Nguyen, M Wang, N Ann Maria, AY Li… - Microsystems & …, 2022 - nature.com
Effective containment of the COVID-19 pandemic requires rapid and accurate detection of
the pathogen. Polymerase chain reaction (PCR) remains the gold standard for COVID-19 …

Recent advancements in nucleic acid detection with microfluidic chip for molecular diagnostics

Z Li, X Xu, D Wang, X Jiang - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) has extensively promoted the
application of nucleic acid testing technology in the field of clinical testing. The most widely …

A sample-to-answer, quantitative real-time PCR system with low-cost, gravity-driven microfluidic cartridge for rapid detection of SARS-CoV-2, influenza A/B, and …

Y Zai, C Min, Z Wang, Y Ding, H Zhao, E Su, N He - Lab on a Chip, 2022 - pubs.rsc.org
The pandemic of coronavirus disease 2019 (COVID-19), due to the novel coronavirus
(SARS-CoV-2), has created an unprecedented threat to the global health system, especially …

Optimized qRT-PCR approach for the detection of intra-and extra-cellular SARS-CoV-2 RNAs

T Toptan, S Hoehl, S Westhaus, D Bojkova… - International journal of …, 2020 - mdpi.com
The novel coronavirus SARS-CoV-2 is the causative agent of the acute respiratory disease
COVID-19, which has become a global concern due to its rapid spread. Meanwhile …

Microfluidic devices for the detection of viruses: Aspects of emergency fabrication during the COVID-19 pandemic and other outbreaks

JA Berkenbrock… - Proceedings of the …, 2020 - royalsocietypublishing.org
Extensive testing of populations against COVID-19 has been suggested as a game-changer
quest to control the spread of this contagious disease and to avoid further disruption in our …

A fully automated centrifugal microfluidic system for sample-to-answer viral nucleic acid testing

F Tian, C Liu, J Deng, Z Han, L Zhang, Q Chen… - Science China …, 2020 - Springer
The outbreak of virus-induced infectious diseases poses a global public-health challenge.
Nucleic acid amplification testing (NAAT) enables early detection of pandemic viruses and …

Automated sample-to-answer centrifugal microfluidic system for rapid molecular diagnostics of SARS-CoV-2

L Malic, D Brassard, D Da Fonte, C Nassif, M Mounier… - Lab on a Chip, 2022 - pubs.rsc.org
Testing for SARS-CoV-2 is one of the most important assets in COVID-19 management and
mitigation. At the onset of the pandemic, SARS-CoV-2 testing was uniquely performed in …

Nucleic acid testing of SARS-CoV-2

HM Yoo, IH Kim, S Kim - International Journal of Molecular Sciences, 2021 - mdpi.com
The coronavirus disease 2019 (COVID-19) has caused a large global outbreak. It is
accordingly important to develop accurate and rapid diagnostic methods. The polymerase …

[HTML][HTML] Advancements in detection of SARS-CoV-2 infection for confronting COVID-19 pandemics

Y Zhou, L Zhang, YH Xie, J Wu - Laboratory investigation, 2022 - Elsevier
As one of the major approaches in combating the COVID-19 pandemics, the availability of
specific and reliable assays for the SARS-CoV-2 viral genome and its proteins is essential to …